Evidence map›Paper›PMID 27261984›Full record

Trial reportComplementary therapies in medicine2016

A yoga & exercise randomized controlled trial for vasomotor symptoms: Effects on heart rate variability.

Salene M W Jones, Katherine A Guthrie, Susan D Reed, Carol A Landis, Barbara Sternfeld, Andrea Z LaCroix, Andrea Dunn, Robert L Burr, Katherine M Newton

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Complementary therapies in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06210412 naunknown statusnot on this mapstarted 2024, after this paper: background citation

The Effect of Health Education and Yoga Practices Given According to Pender's Health Promotion Model on Menopausal Symptoms and Quality of Life: A Randomized Controlled Study

TypeinterventionalSponsorEastern Mediterranean UniversityRan2024 to 2024Enrolled66ConditionsQuality of Life, Health Education, Yoga, Menopause SymptomsArmshealth education and yoga intervention group
NCT06379503 nacompletednot on this mapstarted 2021, after this paper: background citation

Effect of Heart Yoga Applıed To Patıents Undergoıng Cardıovascular Surgery on Sleep, Depressıon And Qualıty of Lıfe

TypeinterventionalSponsorDokuz Eylul UniversityRan2021 to 2023Enrolled60ConditionsCardiac Disease, Yoga, Nursing CariesArmsHEART YOGA, routine nursing care
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Regulation of exercise on heart rate variability in perimenopausal and postmenopausal women.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
  3. CanSports medicine and health science · 2023
    Article
  4. Lights on MsFLASH: a review of contributions.Menopause (New York, N.Y.) · 2020
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Salene M W JonesGroup Health Research Institute, 1730 Minor Ave, Seattle, WA 98101, United States. Electronic address: wu.582@osu.edu.
Katherine A GuthrieFred Hutchinson Cancer Research Center, Seattle, WA, United States.
Susan D ReedDepartment of Obstetrics and Gynecology, University of Washington, Seattle, WA, United States.
Carol A LandisSchool of Nursing, University of Washington, Seattle, WA, United States.
Barbara SternfeldKaiser Permanente Division of Research, Oakland, CA, United States.
Andrea Z LaCroixUniversity of California San Diego, San Diego, CA, United States.
Andrea DunnKaiser Permanente Division of Research, Oakland, CA, United States.
Robert L BurrSchool of Nursing, University of Washington, Seattle, WA, United States.
Katherine M NewtonGroup Health Research Institute, 1730 Minor Ave, Seattle, WA 98101, United States.

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
INDIANA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (UL1): BPCAUL1RR025761 · NCRR · INDIANA UNIVERSITY INDIANAPOLIS · PI SHEKHAR, ANANTHA · 2008 to 2011
$21.0M
Menopausal Symptoms Initiative-Finding Lasting Answers for Sweats and Hot FlashesU01AG032699 · NIA · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GUTHRIE, KATHERINE ADAMS, LACROIX, ANDREA Z. · 2008 to 2012
$13.5M
MsFLASH: Living a Healthy MenopauseR01AG048209 · NIA · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GUTHRIE, KATHERINE ADAMS, LACROIX, ANDREA Z. · 2015 to 2019
$7.2M
MSI-FLASH: Relative Efficacy of Hormonal and Non-Hormonal Interventions for VMSU01AG032700 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI COHEN, LEE S, JOFFE, HADINE · 2008 to 2012
$1.7M
MSI FLASH: An RCT of Yoga and Ultra Low-Dose Estrogen Gel for Vasomotor SymptomsU01AG032682 · NIA · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI NEWTON, KATHERINE M. · 2008 to 2012
$1.7M
Efficacy of an SSRI for Menopausal Symptoms in Perimenopausal WomenU01AG032656 · NIA · UNIVERSITY OF PENNSYLVANIA · PI FREEMAN, ELLEN W · 2008 to 2012
$1.5M
MSI-FLASH: Paced Respiration for Breast Cancer SurvivorsU01AG032659 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI CARPENTER, JANET S · 2008 to 2012
$1.5M
MSI-FLASH: An Exercise Intervention for Women with Menopausal SymptomsU01AG032669 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI CAAN, BETTE J · 2008 to 2012
$1.5M
Health Care Improvement for Aging WomenT32AG027677 · NIA · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI LACROIX, ANDREA Z. · 2007 to 2016
$1.4M
NCATS NIH HHS UL1 TR001108NCRR NIH HHS UL1 RR025761NIA NIH HHS R01 AG048209NIA NIH HHS T32 AG027677NIA NIH HHS U01 AG032656NIA NIH HHS U01 AG032659NIA NIH HHS U01 AG032669NIA NIH HHS U01 AG032682NIA NIH HHS U01 AG032699NIA NIH HHS U01 AG032700
6 · The paper itself

Abstract

objectivesHeart rate variability (HRV) reflects the integration of the parasympathetic nervous system with the rest of the body. Studies on the effects of yoga and exercise on HRV have been mixed but suggest that exercise increases HRV. We conducted a secondary analysis of the effect of yoga and exercise on HRV based on a randomized clinical trial of treatments for vasomotor symptoms in peri/post-menopausal women.

designRandomized clinical trial of behavioral interventions in women with vasomotor symptoms (n=335), 40-62 years old from three clinical study sites.

interventions12-weeks of a yoga program, designed specifically for mid-life women, or a supervised aerobic exercise-training program with specific intensity and energy expenditure goals, compared to a usual activity group.

main outcome measuresTime and frequency domain HRV measured at baseline and at 12 weeks for 15min using Holter monitors.

resultsWomen had a median of 7.6 vasomotor symptoms per 24h. Time and frequency domain HRV measures did not change significantly in either of the intervention groups compared to the change in the usual activity group. HRV results did not differ when the analyses were restricted to post-menopausal women.

conclusionsAlthough yoga and exercise have been shown to increase parasympathetic-mediated HRV in other populations, neither intervention increased HRV in middle-aged women with vasomotor symptoms. Mixed results in previous research may be due to sample differences. Yoga and exercise likely improve short-term health in middle-aged women through mechanisms other than HRV.

Indexed as

Exercise TherapyYogaAdultFemaleHeart RateHumansMenopauseMiddle AgedExerciseHeart rate variabilityHot flashesParasympathetic nervous systemVagal toneYoga

Identifiers

PMID27261984
PMCPMC4893767

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.