Evidence map›Paper›PMID 27261826›Full record

ReviewCardiac electrophysiology clinics2016

Modulation of Cardiac Potassium Current by Neural Tone and Ischemia.

Todd T Tomson, Rishi Arora

Open access · greenAbstract readReview
In one paragraph

Review in Cardiac electrophysiology clinics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Blocking NaBMC cardiovascular disorders · 2024
    Article
  3. Article
  4. Autonomic modulation of ventricular electrical activity: recent developments and clinical implications.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Todd T TomsonBluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Rishi AroraBluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address: r-arora@northwestern.edu.
Cardiovascular Institute of the South · US

Funding

Disruption of Autonomic Pathways in the Left Atrium by Inhibition of G-proteinsR01HL093490 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARORA, RISHI · 2009 to 2013
$2.5M
NHLBI NIH HHS R01 HL093490
6 · The paper itself

Abstract

The cardiac action potential is generated by intricate flows of ions across myocyte cell membranes in a coordinated fashion to control myocardial contraction and the heart rhythm. Modulation of the flow of these ions in response to a variety of stimuli results in changes to the action potential. Abnormal or altered ion currents can result in cardiac arrhythmias. Abnormalities of autonomic regulation of potassium current play a role in the genesis of cardiac arrhythmias, and alterations in acetylcholine-activated potassium channels may play a key role in atrial fibrillation. Ischemia is another important modulator of cardiac cellular electrophysiology.

Indexed as

AnimalsArrhythmias, CardiacAutonomic Nervous SystemCardiac ElectrophysiologyDogsHeartHumansMiceMyocardial IschemiaPotassium ChannelsPotassium ChannelsAcetylcholine-activated potassium channelATP-sensitive potassium channelAtrial fibrillationAutonomic nervous systemCardiac arrhythmiasPotassium channels

Identifiers

PMID27261826
PMCPMC4915363
OpenAlexW2334111347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.