ArticlePreventive medicine2016
Objectively measured physical activity, sedentary time and subclinical vascular disease: Cross-sectional study in older British men.
Article in Preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Pooled it
- Magnesium depletion score is associated with arterial stiffness: data from the Brisighella Heart Study.Journal of hypertension · 2026Article
- Trajectories of total and domain-specific physical activity and vascular structure and function in mid-adulthood: the Childhood Determinants of Adult Health study.European heart journal open · 2026Article
- Association of physical activity, sedentary time, and sleep with maternal vascular function in women with a history of preeclampsia.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Arterial aging and the autonomic nervous system: is the relationship differently modified by physical activity in men and women?Frontiers in aging · 2025Article
- Healthy Eating beyond Whole Grains-Insight on Associations between Diet Quality and Arterial Stiffness in the Brisighella Heart Study Cohort.Nutrients · 2024Article
- Associations of movement behaviours and dietary intake with arterial stiffness: results from the ORISCAV-LUX 2 cross-sectional study.BMJ open · 2024Article
- Relationship between objectively measured physical activity and subclinical cardiovascular disease: a systematic review.BMJ open sport & exercise medicine · 2024Article
- Article
- The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification.Journal of translational medicine · 2023Article
- Device-measured movement behaviors and cardiac biomarkers in older adults without major cardiovascular disease: the Seniors-ENRICA-2 study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023Article
- Self-Reported Coffee Consumption and Central and Peripheral Blood Pressure in the Cohort of the Brisighella Heart Study.Nutrients · 2023Article
- Effect of physical activity on the change in carotid intima-media thickness: An 8-year prospective cohort study.PloS one · 2023Article
- The Role of Physical Activity Status in the Relationship between Obesity and Carotid Intima-Media Thickness (CIMT) in Urban South African Teachers: The SABPA Study.International journal of environmental research and public health · 2022Article
- Sedentary Behaviour and Its Relationship with Early Vascular Ageing in the General Spanish Population: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Article
- Physical activity and carotid atherosclerosis risk reduction in population with high risk for cardiovascular diseases: a cross-sectional study.BMC public health · 2022Article
- Influence of Epoch Length and Recording Site on the Relationship Between Tri-Axial Accelerometry-Derived Physical Activity Levels and Structural, Functional, and Hemodynamic Properties of Central and Peripheral Arteries.Frontiers in sports and active living · 2022Article
- Midlife Cardiorespiratory Fitness and the Development of Peripheral Artery Disease in Later Life.Journal of the American Heart Association · 2021Article
- Agreement Between Self-Reported and Device-Based Sedentary Time among Eight Countries: Findings from the ELANS.Prevention science : the official journal of the Society for Prevention Research · 2021Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
Low physical activity (PA) and high levels of sedentary time (ST) are associated with higher cardiovascular disease (CVD) risk among older people. However, their independent contribution and importance of duration of PA and ST bouts remain unclear. We investigated associations between objectively measured PA, ST and non-invasive vascular measures, markers of CVD risk. Cross-sectional study of 1216 men from the British Regional Heart Study, mean age 78.5years, measured in 2010-2012. Carotid intima thickness (CIMT), distensibility coefficient (DC) and plaque presence were measured using ultrasound; pulse wave velocity (cfPWV) and augmentation index (AIx) using a Vicorder. PA and ST were measured using hip-worn ActiGraph GT3X accelerometers. After adjusting for covariates, each additional 1000 steps per day was associated with a 0.038m/s lower cfPWV (95% CI=-0.076, 0.0003), 0.095 10(-3) kPa(-1) higher DC (95% CI=0.006, 0.185), 0.26% lower AIx (95% CI=-0.40, -0.12) and a 0.005mm lower CIMT (95% CI=-0.008, -0.001). Moderate and vigorous PA (MVPA) was associated with lower AIx and CIMT, light PA (LPA) with lower cfPWV and CIMT and ST with higher cfPWV, AIx and CIMT and lower DC. LPA and ST were highly correlated (r=-0.62). The independence of MVPA and ST or MVPA and LPA was inconsistent across vascular measures. Bout lengths for both PA and ST were not associated with vascular measures. In our cross-sectional study of older men, all PA regardless of intensity or bout duration was beneficially associated with vascular measures, as was lower ST. LPA was particularly relevant for cfPWV and CIMT.
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Registered trials
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