Evidence map›Paper›PMID 27259581›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2016

Stigma as a key determinant of health-related quality of life in Parkinson's disease.

Hui-Ing Ma, Marie Saint-Hilaire, Cathi A Thomas, Linda Tickle-Degnen

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03938974 (The Emergence and Evolution of Social Self-Management of Parkinson's Disease), which is not on this map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03938974 completednot on this map

The Emergence and Evolution of Social Self-Management of Parkinson's Disease

TypeobservationalSponsorTufts UniversityRan2013 to 2019Enrolled146ConditionsParkinson Disease
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Parkinsonian gait improvement through vibratory stride parameter feedback.Journal of neuroengineering and rehabilitation · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Stigma and social symptoms in Parkinson's disease: A scoping review.Clinical parkinsonism & related disorders · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Hui-Ing MaDepartment of Occupational Therapy, College of Medicine, National Cheng Kung University, 1 University Road, Tainan, 701, Taiwan. huingma@mail.ncku.edu.tw.
Marie Saint-HilaireDepartment of Neurology, Parkinson's Disease and Movement Disorders Center, Boston University Medical School, Boston Medical Center, Boston, MA, USA.
Cathi A ThomasDepartment of Neurology, Parkinson's Disease and Movement Disorders Center, Boston University Medical School, Boston Medical Center, Boston, MA, USA.
Linda Tickle-DegnenDepartment of Occupational Therapy, School of Arts and Sciences, Tufts University, Medford, MA, USA.
Boston Medical Center · USBoston University · USNational Cheng Kung University · TWTufts University · US

Funding

Tufts Clinical and Translation Science Institute (UL1)UL1TR000073 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2012 to 2013
$5.5M
Emergence and evolution of social self-management of Parkinsons diseaseR01NR013522 · NINR · TUFTS UNIVERSITY MEDFORD · PI TICKLE-DEGNEN, LINDA S · 2013 to 2017
$2.2M
NCATS NIH HHS UL1 TR000073NINR NIH HHS R01 NR013522
6 · The paper itself

Abstract

purposePeople with Parkinson's disease (PD) may experience stigma due to their visible features of movement and communication difficulties. This paper aimed to examine the role of experienced stigma in health-related quality of life (QOL), after controlling for personal and clinical characteristics.

methodsThis is a preliminary analysis of a subset of baseline data from the Social Self-Management of Parkinson's Disease Study (SocM-PD), an ongoing 3-year prospective cohort study. Seventy-three people with PD (M

resultsSignificant correlations were found between QOL with gender (r = .26), disease severity (r = .38), depression (r = .65), motor difficulties of daily living (r = .71), and stigma (r = .83). After controlling for the significant covariates, stigma made a significant and unique contribution to the explanation of QOL by 13.7 % (p < 0.001). A final hierarchical multiple regression with stigma and the 4 covariates revealed an overall model that explained 77.8 % of the total variance of QOL (F [5, 63] = 48.79, p < 0.001).

conclusionsExperienced stigma appears to be a key determinant of QOL in people with PD. The results suggest the importance of further understanding stigma in PD to develop possible intervention strategies. Future work is also needed to verify the results with a larger and longitudinal dataset of the SocM-PD.

Indexed as

Sickness Impact ProfileAgedCohort StudiesFemaleHumansMaleParkinson DiseaseProspective StudiesEnacted stigmaFelt stigmaHealth-related quality of lifeParkinson’s disease

Identifiers

PMID27259581
PMCPMC5106304
OpenAlexW2463469277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.