ArticleJournal of experimental botany2016
The subtilisin-like protease SBT3 contributes to insect resistance in tomato.
Article in Journal of experimental botany, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- The front line of defence: a meta-analysis of apoplastic proteases in plant immunity.Journal of experimental botany · 2021Pooled it
- Pectin under stress: Pectin methylesterases at the core of cell wall remodeling, integrity sensing, and signaling in plants.Plant communications · 2026Review
- Genome-wide identification, characterization and expression analysis of the subtilisin-like protease gene family in Quercus ilex in response to Phytophthora cinnamomi.Scientific reports · 2026Article
- Quiescence of postharvest pathogens: a fungal inhibition process or an immune response of the unripe host fruit?The New phytologist · 2026Review
- Characteristics and functions of volatile organic compounds in the tripartite symbiotic system ofPlant signaling & behavior · 2024Article
- Pull the fuzes: Processing protein precursors to generate apoplastic danger signals for triggering plant immunity.Plant communications · 2024Review
- Genomic and metabolic profiling of two tomato contrasting cultivars for tolerance to Tuta absoluta.Planta · 2023Article
- A GBS-based genome-wide association study reveals the genetic basis of salinity tolerance at the seedling stage in bread wheat (Frontiers in genetics · 2022Article
- Host susceptibility factors render ripe tomato fruit vulnerable to fungal disease despite active immune responses.Journal of experimental botany · 2021Article
- Changes in the microsomal proteome of tomato fruit during ripening.Scientific reports · 2019Article
- Tissue-specific transcriptomic profiling of Plantago major provides insights for the involvement of vasculature in phosphate deficiency responses.Molecular genetics and genomics : MGG · 2019Article
- Proteomics Analysis Reveals That Caspase-Like and Metacaspase-Like Activities Are Dispensable for Activation of Proteases Involved in Early Response to Biotic Stress inInternational journal of molecular sciences · 2018Article
- The tomato subtilase family includes several cell death-related proteinases with caspase specificity.Scientific reports · 2018Article
- Subtilisin-like proteases in plant defence: the past, the present and beyond.Molecular plant pathology · 2018Review
- Indispensable Role of Proteases in Plant Innate Immunity.International journal of molecular sciences · 2018Review
- Expression analysis of proteinase inhibitor-II under3 Biotech · 2018Article
- The Plastid and Mitochondrial Peptidase Network inThe Plant cell · 2017Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subtilisin-like proteases (SBTs) constitute a large family of extracellular plant proteases, the function of which is still largely unknown. In tomato plants, the expression of SBT3 was found to be induced in response to wounding and insect attack in injured leaves but not in healthy systemic tissues. The time course of SBT3 induction resembled that of proteinase inhibitor II and other late wound response genes suggesting a role for SBT3 in herbivore defense. Consistent with such a role, larvae of the specialist herbivore Manduca sexta performed better on transgenic plants silenced for SBT3 expression (SBT3-SI). Supporting a contribution of SBT3 to systemic wound signaling, systemic induction of late wound response genes was attenuated in SBT3-SI plants. The partial loss of insect resistance may thus be explained by a reduction in systemic defense gene expression. Alternatively, SBT3 may play a post-ingestive role in plant defense. Similar to other anti-nutritive proteins, SBT3 was found to be stable and active in the insect's digestive system, where it may act on unidentified proteins of insect or plant origin. Finally, a reduction in the level of pectin methylesterification that was observed in transgenic plants with altered levels of SBT3 expression suggested an involvement of SBT3 in the regulation of pectin methylesterases (PMEs). While such a role has been described in other systems, PME activity and the degree of pectin methylesterification did not correlate with the level of insect resistance in SBT3-SI and SBT3 overexpressing plants and are thus unrelated to the observed resistance phenotype.
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