ArticleBMJ open2016
Retrospective cross-sectional review of survival rates in critically ill children admitted to a combined paediatric/neonatal intensive care unit in Johannesburg, South Africa, 2013-2015.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Incidence and predictors of mortality among low birth weight neonates in Africa: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Gender differences in survival among low birthweight newborns and infants in sub-Saharan Africa: a systematic review.International health · 2022Pooled it
- Clinical characteristics and outcomes of children admitted to adult intensive care and high-dependency units in Kenya: a multicenter registry-based analysis.Frontiers in pediatrics · 2025Article
- South African pre-hospital emergency care personnel's lived experiences of managing paediatric emergencies: A qualitative research design utilising one-on-one interviews.Health SA = SA Gesondheid · 2021Article
- Short-term outcomes of HIV-exposed and HIV-unexposed preterm, very low birthweight neonates: a longitudinal, hospital-based study.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Quality of Healthcare in Acute Pediatric Care Unit in a Tertiary Hospital in Tanzania: A Case of Muhimbili National Hospital.Frontiers in pediatrics · 2020Article
- Global Critical Care: Moving Forward in Resource-Limited Settings.Annals of global health · 2019Review
- A comparison between raw and predicted mortality in a paediatric intensive care unit in South Africa.BMC research notes · 2018Article
- Epidemiology of Disease and Mortality From a PICU in Mozambique.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018Observational
- The Potential Harm of Cytomegalovirus Infection in Immunocompetent Critically Ill Children.Frontiers in pediatrics · 2018Article
- Review of supplemental oxygen and respiratory support for paediatric emergency care in sub-Saharan Africa.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2017Review
- A review of necrotising enterocolitis in very low birth weight babies in a tertiary hospital in Johannesburg.African journal of paediatric surgery : AJPSReview
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveReport on survival to discharge of children in a combined paediatric/neonatal intensive care unit (PNICU). DESIGN AND
settingRetrospective cross-sectional record review.
participantsAll children (medical and surgical patients) admitted to PNICU between 1 January 2013 and 30 June 2015. OUTCOME MEASURES: Primary outcome-survival to discharge. Secondary outcomes-disease profiles and predictors of mortality in different age categories.
resultsThere were 1454 admissions, 182 missing records, leaving 1272 admissions for review. Overall mortality rate was 25.7% (327/1272). Mortality rate was 41.4% (121/292) (95% CI 35.8% to 47.1%) for very low birthweight (VLBW) babies, 26.6% (120/451) (95% CI 22.5% to 30.5%) for bigger babies and 16.2% (86/529) (95% CI 13.1% to 19.3%) for paediatric patients. Risk factors for a reduced chance of survival to discharge in paediatric patients included postcardiac arrest (OR 0.21, 95% CI 0.09 to 0.49), inotropic support (OR 0.085, 95% CI 0.04 to 0.17), hypernatraemia (OR 0.16, 95% CI 0.04 to 0.6), bacterial sepsis (OR 0.32, 95% CI 0.16 to 0.65) and lower respiratory tract infection (OR 0.54, 95% CI 0.30 to 0.97). Major birth defects (OR 0.44, 95% CI 0.26 to 0.74), persistent pulmonary hypertension of the new born (OR 0.44, 95% CI 0.21 to 0.91), metabolic acidosis (OR 0.23, 95% CI 0.12 to 0.74), inotropic support (OR 0.23, 95% CI 0.12 to 0.45) and congenital heart defects (OR 0.29, 95% CI 0.13 to 0.62) predicted decreased survival in bigger babies. Birth weight (OR 0.997, 95% CI 0.995 to 0.999), birth outside the hospital (OR 0.21, 95% CI 0.05 to 0.84), HIV exposure (OR 0.54, 95% CI 0.30 to 0.99), resuscitation at birth (OR 0.49, 95% CI 0.25 to 0.94), metabolic acidosis (OR 0.25, 95% CI 0.10 to 0.60) and necrotising enterocolitis (OR 0.23, 95% CI 0.12 to 0.46) predicted poor survival in VLBW babies.
conclusionsOngoing mortality review is essential to improve provision of paediatric critical care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.