The Epidemiology of Leber Hereditary Optic Neuropathy in the North East of England.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Cell-intrinsic vulnerability and immune activation cooperate to drive degeneration in a mitochondrial complex I deficiency model of optic neuropathy.Journal of neuroinflammation · 2026
   Article
2. Clinical Features of Leber Hereditary Optic Neuropathy Carrying a Rare m.13051G>A Mitochondrial Mutation: A Case Report.Korean journal of ophthalmology : KJO · 2025
   Article
3. An exploratory study to evaluate efficacy and safety of frequent Transcutaneous Electrical Stimulation for Leber Hereditary Optic Neuropathy.Scientific reports · 2025
   Article
4. New Insights into Mitochondria in Health and Diseases.International journal of molecular sciences · 2024
   Review
5. Proteomic Profiling Reveals Increased Glycolysis, Decreased Oxidoreductase Activity and Fatty Acid Degradation in Skin Derived Fibroblasts from LHON Patients Bearing m.G11778A.Biomolecules · 2022
   Article
6. Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy.Cell reports · 2022
   Article
7. Benefit of Stimulus Size V Perimetry for Patients With a Dense Central Scotoma From Leber's Hereditary Optic Neuropathy.Translational vision science & technology · 2021
   Article
8. Characteristics of Japanese patients with Leber's hereditary optic neuropathy and idebenone trial: a prospective, interventional, non-comparative study.Japanese journal of ophthalmology · 2021
   Article
9. Mutation spectrum of the OPA1 gene in a large cohort of patients with suspected dominant optic atrophy: Identification and classification of 48 novel variants.PloS one · 2021
   Article
10. Retinal Ganglion Cells-Diversity of Cell Types and Clinical Relevance.Frontiers in neurology · 2021
    Review
11. Juvenile open-angle Glaucoma associated with Leber's hereditary optic neuropathy: a case report and literature review.BMC ophthalmology · 2018
    Review

Corrections and comments

• Erratum for
  The epidemiology of Leber hereditary optic neuropathy in the North East of England.2003

Authors and funding

5 authors.

Funding

Abstract

PubMed holds no abstract for this paper.