ArticlePloS one2016
Towards Sustainable Aquafeeds: Complete Substitution of Fish Oil with Marine Microalga Schizochytrium sp. Improves Growth and Fatty Acid Deposition in Juvenile Nile Tilapia (Oreochromis niloticus).
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 223 citations in OpenAlex.
- Benefits of the microalgae Spirulina and Schizochytrium in fish nutrition: a meta-analysis.Scientific reports · 2023Pooled it
- Article
- Effects of a Mixed Biomass of Thalassiosira weissflogii and Chaetoceros calcitrans as a Functional Feed Additive for Pacific White Shrimp (Penaeus vannamei).Marine biotechnology (New York, N.Y.) · 2026Article
- Supplementing the diet of Nile tilapia (Oreochromis niloticus) with microalgae Nannochloropsis oculata and Phaeodactylum tricornutum enhanced immune function, lipid profile, and resistance to Edwardsiella tarda infection.Veterinary research communications · 2026Article
- Evaluation of Biorefinery Products FromAquaculture nutrition · 2026Article
- DHA-Rich Algae Feed Modulates Atlantic Salmon Health, Microbiota and Stress Response.Aquaculture nutrition · 2026Article
- The Quest for Functional Ingredients for Sustainable Aquaculture Feeds in Sub-Saharan Africa.Aquaculture nutrition · 2026Review
- Article
- Effect of shrimp head lipid extract on growth, body composition, tissue and feed antioxidant parameters, and serum profile of nile tilapia (Oreochromis niloticus).Tropical animal health and production · 2025Article
- Impact of Alternative Feed Ingredients and Feeding Strategies on Growth, Muscle Morphology, and Fillet Quality of Genetically Selected Gilthead Seabream (Animals : an open access journal from MDPI · 2025Article
- DietaryAnimals : an open access journal from MDPI · 2025Article
- Towards Sustainable Aquafeeds: Microalgal (Foods (Basel, Switzerland) · 2025Article
- A review of marine microalgae-based lipids production: biosynthesis, technological advancements, and practical applications.Frontiers in nutrition · 2025Review
- Exploring Protein-Based Fishmeal Alternatives for Aquaculture Feeds in Bangladesh.Aquaculture nutrition · 2025Review
- A Pretty Kettle of Fish: A Review on the Current Challenges in Mediterranean Teleost Reproduction.Animals : an open access journal from MDPI · 2024Review
- Dietary Effects of a Short-Term Administration of Microalgae Blend on Growth Performance, Tissue Fatty Acids, and Predominant Intestinal Microbiota inMicroorganisms · 2023Article
- Microorganisms in Fish Feeds, Technological Innovations, and Key Strategies for Sustainable Aquaculture.Microorganisms · 2023Review
- Fishmeal, plant protein, and fish oil substitution with single-cell ingredients in organic feeds for European sea bass (Frontiers in physiology · 2023Article
- Protective mechanisms of a microbial oil against hypercholesterolemia: evidence from a zebrafish model.Frontiers in nutrition · 2023Article
- Aquaculture sustainability through alternative dietary ingredients: Microalgal value-added products.Engineering microbiology · 2022Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We conducted a 84-day nutritional feeding experiment with dried whole cells of DHA-rich marine microalga Schizochytrium sp. (Sc) to determine the optimum level of fish-oil substitution (partial or complete) for maximum growth of Nile tilapia. When we fully replaced fish oil with Schizochytrium (Sc100 diet), we found significantly higher weight gain and protein efficiency ratio (PER), and lower (improved) feed conversion ratio (FCR) and feed intake compared to a control diet containing fish oil (Sc0); and no significant change in SGR and survival rate among all diets. The Sc100 diet had the highest contents of 22:6n3 DHA, led to the highest DHA content in fillets, and consequently led to the highest DHA:EPA ratios in tilapia fillets. Schizochytrium sp. is a high quality candidate for complete substitution of fish oil in juvenile Nile tilapia feeds, providing an innovative means to formulate and optimize the composition of tilapia juvenile feed while simultaneously raising feed efficiency of tilapia aquaculture and to further develop environmentally and socially sustainable aquafeeds. Results show that replacing fish oil with DHA-rich marine Sc improves the deposition of n3 LC PUFA levels in tilapia fillet. These results support further studies to lower Schizochytrium production costs and to combine different marine microalgae to replace fish oil and fishmeal into aquafeeds.
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