Evidence map›Paper›PMID 27258294›Full record

Trial reportInternational journal of environmental research and public health2016

Tracking Restoration of Park and Urban Street Settings in Coronary Artery Disease Patients.

Regina Grazuleviciene, Jone Vencloviene, Raimondas Kubilius, Vytautas Grizas, Asta Danileviciute, Audrius Dedele, Sandra Andrusaityte, Astra Vitkauskiene, Rasa Steponaviciute, Mark J Nieuwenhuijsen

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04324203 (The Effectiveness of 3DVR Horticultural Therapy on Older Adults' Physical and Mental Health), which is not on this map. Cited by 33 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04324203 nacompletednot on this mapstarted 2018, after this paper: background citation

The Effectiveness of 3DVR Horticultural Therapy on Older Adults' Physical and Mental Health

TypeinterventionalSponsorNational Taiwan Normal UniversityRan2018 to 2019Enrolled106ConditionsPhysical Health, Mental HealthArmsThree-dimensional Virtual Reality and Horticultural Therapy
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Investigation of Epistemic Equity in Urban Green Space and Mental Health Research: A Systematic Review.International journal of environmental research and public health · 2026
    Pooled it
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  4. What Activities in Forests Are Beneficial for Human Health? A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Regina GrazulevicieneDepartment of Environmental Science, Vytauto Didziojo Universitetas, K. Donelaicio 58, Kaunas 44248, Lithuania. r.grazuleviciene@gmf.vdu.lt.
Jone VenclovieneDepartment of Environmental Science, Vytauto Didziojo Universitetas, K. Donelaicio 58, Kaunas 44248, Lithuania. j.vencloviene@gmf.vdu.lt.
Raimondas KubiliusDepartment of Cardiology, Medical Academy, Lietuvos Sveikatos Mokslu Universitetas, Eivenių 2, Kaunas 50161, Lithuania. raimondas@efarmacija.lt.
Vytautas GrizasInstitute of Cardiology, Medical Academy, Lietuvos Sveikatos Mokslu Universitetas, Kaunas 50161, Lithuania. vytautasgri@gmail.com.
Asta DanileviciuteDepartment of Environmental Science, Vytauto Didziojo Universitetas, K. Donelaicio 58, Kaunas 44248, Lithuania. a.danileviciute@gmf.vdu.lt.
Audrius DedeleDepartment of Environmental Science, Vytauto Didziojo Universitetas, K. Donelaicio 58, Kaunas 44248, Lithuania. a.dedele@gmf.vdu.lt.
Sandra AndrusaityteDepartment of Environmental Science, Vytauto Didziojo Universitetas, K. Donelaicio 58, Kaunas 44248, Lithuania. s.andrusaityte@gmf.vdu.lt.
Astra VitkauskieneDepartment of Laboratory Medicine, Medical Academy, Lietuvos Sveikatos Mokslu Universitetas, Eiveniu Str. 2, Kaunas 50028, Lithuania. astra.vitkauskiene@kaunoklinikos.lt.
Rasa SteponaviciuteDepartment of Laboratory Medicine, Medical Academy, Lietuvos Sveikatos Mokslu Universitetas, Eiveniu Str. 2, Kaunas 50028, Lithuania. rasastepkons@gmail.com.
Mark J NieuwenhuijsenCentre for Research in Environmental Epidemiology (CREAL), Doctor Aiguader 88, Barcelona 08003, Spain. mnieuwenhuijsen@creal.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledThe physiological effects of natural and urban environments on the cardiovascular system of coronary artery disease (CAD) patients are not fully understood. This controlled field study examines the effects of restorative walking in a park vs. in an urban street environment on CAD patients' stress parameters and cardiac function.

methodsTwenty stable CAD patients were randomly allocated to 7 days controlled walking in a city park or in an urban street environment group. The relationship between different environmental exposures and health effects was analyzed using Wilcoxon signed-rank test and exact Mann-Whitney U test.

resultsThe mean reduction in cortisol levels and negative effects after the walk on the first day was greater in the city park than in the urban street exposed group, while a reduction in negative effects in the urban group were greater after seven days. The reduction in diastolic blood pressure (DBP) in the park group was evident on the seventh day before the walk (-4 mm Hg, p = 0.031) and 60 min after the walk (-6.00 mm Hg, p = 0.002). The cortisol slope was negatively associated with the DBP changes (r = -0.514, p < 0.05).

conclusionsPhysical activity in a green environment with noise and air pollution levels lower than in an urban environment has a greater positive effect on CAD patients' stress level and hemodynamic parameters. Mitigating green environmental influences may allow urban residents to maintain health and reduce disability.

Indexed as

CitiesCoronary Artery DiseaseEnvironment DesignParks, RecreationalUrban RenewalAgedEnvironmental ExposureExerciseFemaleHemodynamicsHumansHydrocortisoneLithuaniaMaleMiddle AgedWalkingHydrocortisonecardiovascular diseasecortisolgreen spacehemodynamic parametersphysical activityurban environment

Identifiers

PMID27258294
PMCPMC4924007

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.