ArticleMolecules (Basel, Switzerland)2016
Coffee Silverskin Extract Protects against Accelerated Aging Caused by Oxidative Agents.
Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 75 citations in OpenAlex.
- Coffee By-Products: An Overview of Their Antimicrobial Properties.Molecules (Basel, Switzerland) · 2026Review
- Development of a Hop Functional Analog Derived from a Global Agrofood By-Product: Roasted Coffee Silverskin.Molecules (Basel, Switzerland) · 2026Article
- Extracellular Vesicles Derived from Natural Biological Resources and Their Potential to Facilitate Skin Regeneration and Rejuvenation.Pharmaceutics · 2026Review
- Exploring the Dermatological Benefits of Coffee Extracts and Their Derivatives.Antioxidants (Basel, Switzerland) · 2026Review
- Hybrid Biocomposites Based on Chitosan/Gelatin with Coffee Silverskin Extracts as Promising Biomaterials for Advanced Applications.Polymers · 2025Article
- Fermentation to Increase the Value of Roasted Coffee Silverskin as a Functional Food Ingredient.Foods (Basel, Switzerland) · 2025Article
- Valorization of Food Waste: Extracting Bioactive Compounds for Sustainable Health and Environmental Solutions.Antioxidants (Basel, Switzerland) · 2025Review
- Efficacy of nutraceutical supplements containingFrontiers in veterinary science · 2025Article
- Age Is Just a Number: Progress and Obstacles in the Discovery of New Candidate Drugs for Sarcopenia.Cells · 2023Review
- Coffee Silverskin Phytocompounds as a Novel Anti-Aging Functional Food: A Pharmacoinformatic Approach Combined with In Vitro Study.Molecules (Basel, Switzerland) · 2023Article
- Toxicological Assessment of Roasted Coffee Silver Skin (Testa ofMolecules (Basel, Switzerland) · 2022Review
- Composition of Nonextractable Polyphenols from Sweet Cherry Pomace Determined by DART-Orbitrap-HRMS and TheirJournal of agricultural and food chemistry · 2022Article
- Mulberry polyphenol extracts attenuated senescence through inhibition of Ras/ERK via promoting Ras degradation in VSMC.International journal of medical sciences · 2022Article
- Coffee By-Products and Their Suitability for Developing Active Food Packaging Materials.Foods (Basel, Switzerland) · 2021Review
- Application of adipose-derived stem cells in photoaging: basic science and literature review.Stem cell research & therapy · 2020Review
- Applications of Compounds from Coffee Processing By-Products.Biomolecules · 2020Review
- Chemical Composition, Antioxidant and Enzyme Inhibitory Properties of Different Extracts Obtained from Spent Coffee Ground and Coffee Silverskin.Foods (Basel, Switzerland) · 2020Article
- An Assessment of the Bioactivity of Coffee Silverskin Melanoidins.Foods (Basel, Switzerland) · 2019Article
- Bioprospecting the Solar Panel Microbiome: High-Throughput Screening for Antioxidant Bacteria in aFrontiers in microbiology · 2019Article
- Protective effects of Scutellaria baicalensis Georgi extract on D-galactose induced aging rats.Metabolic brain disease · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nowadays, coffee beans are almost exclusively used for the preparation of the beverage. The sustainability of coffee production can be achieved introducing new applications for the valorization of coffee by-products. Coffee silverskin is the by-product generated during roasting, and because of its powerful antioxidant capacity, coffee silverskin aqueous extract (CSE) may be used for other applications, such as antiaging cosmetics and dermaceutics. This study aims to contribute to the coffee sector's sustainability through the application of CSE to preserve skin health. Preclinical data regarding the antiaging properties of CSE employing human keratinocytes and Caenorhabditis elegans are collected during the present study. Accelerated aging was induced by tert-butyl hydroperoxide (t-BOOH) in HaCaT cells and by ultraviolet radiation C (UVC) in C. elegans. Results suggest that the tested concentrations of coffee extracts were not cytotoxic, and CSE 1 mg/mL gave resistance to skin cells when oxidative damage was induced by t-BOOH. On the other hand, nematodes treated with CSE (1 mg/mL) showed a significant increased longevity compared to those cultured on a standard diet. In conclusion, our results support the antiaging properties of the CSE and its great potential for improving skin health due to its antioxidant character associated with phenols among other bioactive compounds present in the botanical material.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.