Evidence map›Paper›PMID 27258047›Full record

ArticlePloS one2016

MR Imaging of Pulmonary Nodules: Detection Rate and Accuracy of Size Estimation in Comparison to Computed Tomography.

Andrzej Cieszanowski, Antonina Lisowska, Marta Dabrowska, Piotr Korczynski, Malgorzata Zukowska, Ireneusz P Grudzinski, Ryszard Pacho, Olgierd Rowinski, Rafal Krenke

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Guideline
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  9. New developments in the imaging of lung cancer.Breathe (Sheffield, England) · 2024
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  13. Detection of solid and subsolid pulmonary nodules with lung MRI: performance of UTE, T1 gradient-echo, and single-shot T2 fast spin echo.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Article
  14. Same-day comparative protocol PET/CT-PET/MRI [Cancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Article
  15. Article
  16. State-of-the-art MR Imaging for Thoracic Diseases.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Andrzej Cieszanowski2nd Department of Clinical Radiology, Medical University of Warsaw, Central Clinical Hospital, Warsaw, Poland.
Antonina Lisowska2nd Department of Clinical Radiology, Medical University of Warsaw, Central Clinical Hospital, Warsaw, Poland.
Marta DabrowskaDepartment of Internal Medicine, Pneumonology and Allergology, Medical University of Warsaw, Warsaw, Poland.
Piotr KorczynskiDepartment of Internal Medicine, Pneumonology and Allergology, Medical University of Warsaw, Warsaw, Poland.
Malgorzata Zukowska2nd Department of Clinical Radiology, Medical University of Warsaw, Central Clinical Hospital, Warsaw, Poland.
Ireneusz P GrudzinskiDepartment of Toxicology, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
Ryszard Pacho2nd Department of Clinical Radiology, Medical University of Warsaw, Central Clinical Hospital, Warsaw, Poland.
Olgierd Rowinski2nd Department of Clinical Radiology, Medical University of Warsaw, Central Clinical Hospital, Warsaw, Poland.
Rafal KrenkeDepartment of Internal Medicine, Pneumonology and Allergology, Medical University of Warsaw, Warsaw, Poland.
Medical University of Warsaw · PLCentral Clinical Hospital · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aims of this study were to assess the sensitivity of various magnetic resonance imaging (MRI) sequences for the diagnosis of pulmonary nodules and to estimate the accuracy of MRI for the measurement of lesion size, as compared to computed tomography (CT).

methodsFifty patients with 113 pulmonary nodules diagnosed by CT underwent lung MRI and CT. MRI studies were performed on 1.5T scanner using the following sequences: T2-TSE, T2-SPIR, T2-STIR, T2-HASTE, T1-VIBE, and T1-out-of-phase. CT and MRI data were analyzed independently by two radiologists.

resultsThe overall sensitivity of MRI for the detection of pulmonary nodules was 80.5% and according to nodule size: 57.1% for nodules ≤4mm, 75% for nodules >4-6mm, 87.5% for nodules >6-8mm and 100% for nodules >8mm. MRI sequences yielded following sensitivities: 69% (T1-VIBE), 54.9% (T2-SPIR), 48.7% (T2-TSE), 48.7% (T1-out-of-phase), 45.1% (T2-STIR), 25.7% (T2-HASTE), respectively. There was very strong agreement between the maximum diameter of pulmonary nodules measured by CT and MRI (mean difference -0.02 mm; 95% CI -1.6-1.57 mm; Bland-Altman analysis).

conclusionsMRI yielded high sensitivity for the detection of pulmonary nodules and enabled accurate assessment of their diameter. Therefore it may be considered an alternative to CT for follow-up of some lung lesions. However, due to significant number of false positive diagnoses, it is not ready to replace CT as a tool for lung nodule detection.

Indexed as

AgedFemaleHumansLungMagnetic Resonance ImagingMaleMultiple Pulmonary NodulesSolitary Pulmonary NoduleTomography, X-Ray Computed

Identifiers

PMID27258047
PMCPMC4892605
OpenAlexW2418432562

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.