ArticlePloS one2016
The Relationship between Personality Traits, the 5HTT Polymorphisms, and the Occurrence of Anxiety and Depressive Symptoms in Elite Athletes.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Polymorphisms of the serotonin receptors genes in patients with bruxism: a systematic review.Journal of applied oral science : revista FOB · 2022Pooled it
- Determinants of anxiety in elite athletes: a systematic review and meta-analysis.British journal of sports medicine · 2019Pooled it
- What Does Personality Mean in the Context of Mental Health? A Topic Modeling Approach Based on Abstracts Published in Pubmed Over the Last 5 Years.Frontiers in psychiatry · 2019Pooled it
- Sudden cardiac death in young adults and the role of antipsychotic drugs: a multicenter autopsy study.Forensic science, medicine, and pathology · 2026Article
- The influence of athletes' personality traits on competition performance: the multiple mediating effects of competitive anxiety, perfectionism, and stressors.Frontiers in psychology · 2025Article
- Key personality and training factors influencing athletes' mental health - based on machine learning.PloS one · 2025Article
- Intricate mechanism of anxiety disorder, recognizing the potential role of gut microbiota and therapeutic interventions.Metabolic brain disease · 2024Review
- Burnout and Stress in Forensic Science Jobs: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- Multiple sclerosis and personality traits: associations with depression and anxiety.European journal of medical research · 2024Article
- Neurobiology and medico-legal aspects of suicides among older adults: a narrative review.Frontiers in psychiatry · 2024Review
- Using a socioecological approach to explore healthy lifestyle in elite sport: a qualitative study of French athletes', coaches', and managers' perspectives.International journal of qualitative studies on health and well-being · 2023Article
- Psychobiological screening among patients affected by prostate cancer: Identification of potential psychobiological markers.Industrial psychiatry journal · 2023Article
- Review
- Personality traits as mediators in the association betweenFrontiers in psychiatry · 2023Article
- Article
- The Athlete's Paradox: Adaptable Depression.Sports (Basel, Switzerland) · 2022Article
- Associations Between Personality Traits, Perceived Stress and Depressive Symptoms in Gynecological Cancer Patients Characterized by the Short and Long Allele Variant of the 5-HTTLPR Genotype: Preliminary Results.Clinical neuropsychiatry · 2022Article
- Article
- Relationships between Risk Events, Personality Traits, and Risk Perception of Adolescent Athletes in Sports Training.International journal of environmental research and public health · 2021Article
- Sensation-Seeking and Impulsivity in Athletes with Sport-Related Concussion.Current psychiatry reports · 2021Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to determine the relationship between personality, the serotonin transporter (5HTT) polymorphisms and the occurrence of anxiety and depressive symptoms in elite athletes. 133 healthy participants completed the NEO Five-Factor Inventory (NEO-FFI). The mood states were assessed using the Profile of Mood States (POMS) questionnaire. The athlete's mental skills were assessed through the Sport Performance Psychological Inventory (IPPS-48). The occurrence of psychiatric and personality disorders was assessed using the Clinical Interview for DSM-IV Disorders. A polymerase chain reaction was employed to identify genotypes at the 5HTTLPR polymorphism. The 5HTTLPR s/s genotype was associated with both neuroticism (p< 0.001) and tension/anxiety symptoms according to the POMS (p<0.02), cognitive anxiety and emotional arousal control according to the IPPS-48 (p<0.01). Significant correlations were proved between neuroticism and symptoms of anxiety and depression (p<0.05). Neuroticism mediates the association between the 5HTTLPR polymorphism and symptoms of cognitive anxiety and emotional arousal control (p<0.05). These results suggest a significant interaction between the 5HTTLPR polymorphism, neuroticism and sport related stress that predict adverse mental health outcomes in athletes. Identification of homogeneous groups of athletes having predispositions to anxiety and depressive symptoms may help to implement early prevention programs.
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