Evidence map›Paper›PMID 27257648›Full record

ArticleThe Journal of general virology2015

The proteome of the infectious bronchitis virus Beau-R virion.

Stuart D Dent, Dong Xia, Jonathan M Wastling, Benjamin W Neuman, Paul Britton, Helena J Maier

Open access · hybridAbstract read
In one paragraph

Article in The Journal of general virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Veterinary research forum : an international quarterly journal · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Genomewide CRISPR knockout screen identified PLAC8 as an essential factor for SADS-CoVs infection.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Stuart D DentCompton Laboratory, Compton, The Pirbright Institute, Newbury RG20 7NN, UK.
Dong XiaInstitute of Infection and Global Health, University of Liverpool, Liverpool L3 5RF, UK.
Jonathan M WastlingInstitute of Infection and Global Health, University of Liverpool, Liverpool L3 5RF, UK.
Benjamin W NeumanSchool of Biological Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, UK.
Paul BrittonCompton Laboratory, Compton, The Pirbright Institute, Newbury RG20 7NN, UK.
Helena J MaierCompton Laboratory, Compton, The Pirbright Institute, Newbury RG20 7NN, UK.
The Pirbright Institute · GBKeele University · GBUniversity of Liverpool · GBUniversity of Reading · GB

Funding

Biotechnology and Biological Sciences Research Council BB/H01425X/1
6 · The paper itself

Abstract

Infectious bronchitis is a highly contagious respiratory disease of poultry caused by the coronavirus infectious bronchitis virus (IBV). It was thought that coronavirus virions were composed of three major viral structural proteins until investigations of other coronaviruses showed that the virions also include viral non-structural and genus-specific accessory proteins as well as host-cell proteins. To study the proteome of IBV virions, virus was grown in embryonated chicken eggs, purified by sucrose-gradient ultracentrifugation and analysed by mass spectrometry. Analysis of three preparations of purified IBV yielded the three expected structural proteins plus 35 additional virion-associated host proteins. The virion-associated host proteins had a diverse range of functional attributions, being involved in cytoskeleton formation, RNA binding and protein folding pathways. Some of these proteins were unique to this study, while others were found to be orthologous to proteins identified in severe acute respiratory syndrome coronavirus virions and also virions from a number of other RNA and DNA viruses.

Indexed as

AllantoisAnimalsChick EmbryoGene Expression Regulation, ViralInfectious bronchitis virusMass SpectrometryProteomeSpecific Pathogen-Free OrganismsViral ProteinsVirionProteomeViral Proteins

Identifiers

PMID27257648
PMCPMC5410111
OpenAlexW1945490389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.