Evidence map›Paper›PMID 27257272›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2016

Smoking patterns and chronic kidney disease in US Hispanics: Hispanic Community Health Study/Study of Latinos.

Nora Franceschini, Yu Deng, Michael F Flessner, John H Eckfeldt, Holly J Kramer, James P Lash, David J Lee, Michal L Melamed, Ashley E Moncrieft, Ana C Ricardo and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Genome-Wide Association Study of Heavy Smoking and Daily/Nondaily Smoking in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Nora FranceschiniDepartment of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
Yu DengCollaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Michael F FlessnerNational Institute of Diabetes, Digestive, and Kidney Disease, Bethesda, MD, USA.
John H EckfeldtDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.
Holly J KramerDivision of Nephrology, Loyola University, Maywood, IL, USA.
James P LashDepartment of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
David J LeeUniversity of Miami, Miami, FL, USA.
Michal L MelamedAlbert Einstein College of Medicine, New York, NY, USA.
Ashley E MoncrieftUniversity of Miami, Miami, FL, USA.
Ana C RicardoDepartment of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
Sylvia E RosasJoslin Diabetes Center, Harvard University, Boston, MA, USA.
Robert C KaplanAlbert Einstein College of Medicine, New York, NY, USA.
Leopoldo RaijUniversity of Miami, Miami, FL, USA.
Jianwen CaiCollaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
University of Miami · USUniversity of North Carolina at Chapel Hill · USAlbert Einstein College of Medicine · USUniversity of Illinois Chicago · USHarvard University · USLoyola University Chicago · USNational Institute of Diabetes and Digestive and Kidney Diseases · USUniversity of Minnesota · US

Funding

Thalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6M
Health Disparities in Chronic Kidney Disease Mentoring ProgramK24DK092290 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LASH, JAMES P. · 2012 to 2022
$1.9M
GENETIC ARCHITECTURE OF PLASMA T-PA AND PAI-1R01HL065234 · NHLBI · VANDERBILT UNIVERSITY · PI MOORE, JASON H. · 2000 to 2004
$1.7M
Gender Disparities and Vascular Function in Chronic Kidney Disease OutcomesK23DK094829 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RICARDO, ANA CATHERINE · 2013 to 2017
$800k
Trans-ethnic meta-analysis of blood pressure in African and European ancestriesR21HL123677 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRANCESCHINI, NORA · 2014 to 2015
$242k
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS R21 HL123677NIDDK NIH HHS K23 DK094829NIDDK NIH HHS K24 DK092290
6 · The paper itself

Abstract

backgroundIntermittent smoking is prevalent among Hispanics, but little is known about whether this smoking pattern associates with increased chronic kidney disease (CKD) risk in this population. The objective of the present study is to identify patterns of exposure associated with CKD in US Hispanics.

methodsWe used cross-sectional data on 15 410 participants of the Hispanics Community Health Study/the Study of Latinos, a population-based study of individuals aged 18-74 years, recruited in 2008 to 2011 from four US field centers (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA). Smoking exposure was obtained through a questionnaire. CKD was defined by an estimated glomerular filtration rate of <60 mL/min/1.73 m(2) or a urine albumin-to-creatinine ratio of ≥30 mg/g.

resultsApproximately 14% of individuals were daily and 7% were intermittent smokers, and 16% were past smokers. There was a significant interaction between smoking status and pack-years of exposure (P = 0.0003). In adjusted models, there was an increased odds of CKD among daily, intermittent and past smokers by pack-years compared with never smokers. The association of intermittent smokers was significant at 10 pack-years [odds ratio (OR) = 1.38, 95% confidence intervals (CI) 1.06, 1.81], whereas for daily smokers this association was observed at 40 pack-years (OR = 1.43, 95% CI 1.09, 1.89).

conclusionsOur findings of increased risk of CKD among Hispanics who are intermittent smokers support screening and smoking cessation interventions targeted to this population for the prevention of CKD. It also suggests novel mechanistic pathways for kidney toxicity that should be further explored in future studies.

Indexed as

AdolescentAdultAgedCross-Sectional StudiesFemaleHispanic or LatinoHumansMaleMiddle AgedOdds RatioPrevalenceRenal Insufficiency, ChronicRisk FactorsSmokingSurveys and QuestionnairesUnited Stateschronic kidney diseaseHispanics/Latinosintermittent smoking

Identifiers

PMID27257272
PMCPMC5039342
OpenAlexW2410520182

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.