ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2016
Treatment Preferences for Active Surveillance versus Active Treatment among Men with Low-Risk Prostate Cancer.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Factors Influencing Men's Choice of and Adherence to Active Surveillance for Low-risk Prostate Cancer: A Mixed-method Systematic Review.European urology · 2018Pooled it
- Concordance between influential adverse treatment outcomes and localized prostate cancer treatment decisions.BMC medical informatics and decision making · 2022Trial
- Key Determinants Influencing Treatment Decision-Making for and Adherence to Active Surveillance for Prostate Cancer: A Systematic Review.Journal of personalized medicine · 2025Review
- The Safety and Efficacy of Vascular-Targeted Photodynamic Therapy in Low-Risk Prostate Cancer.Cancers · 2025Article
- Active surveillance versus treatment in low-risk DCIS: Women's preferences in the LORD-trial.European journal of cancer (Oxford, England : 1990) · 2023Article
- Planning and developing a web-based intervention for active surveillance in prostate cancer: an integrated self-care programme for managing psychological distress.Pilot and feasibility studies · 2022Article
- Article
- Barriers and facilitators to mobile health and active surveillance use among older adults with skin disease.Health expectations : an international journal of public participation in health care and health policy · 2021Article
- Treatment decision-making in men with localized prostate cancer living in a remote area: A cross-sectional, observational study.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021Article
- Comparing Perspectives of Canadian Men Diagnosed With Prostate Cancer and Health Care Professionals About Active Surveillance.Journal of patient experience · 2020Article
- Radiotherapy for elder patients aged ≥80 with clinically localized prostate cancer - Brachytherapy enhanced late GU toxicity especially in elderly.Clinical and translational radiation oncology · 2020Article
- Selecting Active Surveillance: Decision Making Factors for Men with a Low-Risk Prostate Cancer.Medical decision making : an international journal of the Society for Medical Decision Making · 2019Article
- Appraising risk in active surveillance of localized prostate cancer.Health expectations : an international journal of public participation in health care and health policy · 2019Article
- Why men with a low-risk prostate cancer select and stay on active surveillance: A qualitative study.PloS one · 2019Article
- Percutaneous MR-guided prostate cancer cryoablation technical updates and literature review.BJR open · 2019Review
- Discussing Conservative Management With Older Patients With CKD: An Interview Study of Nephrologists.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018Article
- Prostate Cancer Patient Characteristics Associated With a Strong Preference to Preserve Sexual Function and Receipt of Active Surveillance.Journal of the National Cancer Institute · 2018Article
- Quality of life among men with low-risk prostate cancer during the first year following diagnosis: the PREPARE prospective cohort study.Translational behavioral medicine · 2018Article
- Quality of life in active surveillance and the associations with decision-making-a literature review.Translational andrology and urology · 2018Review
- Decision-making processes among men with low-risk prostate cancer: A survey study.Psycho-oncology · 2018Article
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Abstract
backgroundDue to the concerns about the overtreatment of low-risk prostate cancer, active surveillance (AS) is now a recommended alternative to the active treatments (AT) of surgery and radiotherapy. However, AS is not widely utilized, partially due to psychological and decision-making factors associated with treatment preferences.
methodsIn a longitudinal cohort study, we conducted pretreatment telephone interviews (N = 1,140, 69.3% participation) with newly diagnosed, low-risk prostate cancer patients (PSA ≤ 10, Gleason ≤ 6) from Kaiser Permanente Northern California. We assessed psychological and decision-making variables, and treatment preference [AS, AT, and No Preference (NP)].
resultsMen were 61.5 (SD, 7.3) years old, 24 days (median) after diagnosis, and 81.1% white. Treatment preferences were: 39.3% AS, 30.9% AT, and 29.7% NP. Multinomial logistic regression revealed that men preferring AS (vs. AT) were older (OR, 1.64; CI, 1.07-2.51), more educated (OR, 2.05; CI, 1.12-3.74), had greater prostate cancer knowledge (OR, 1.77; CI, 1.43-2.18) and greater awareness of having low-risk cancer (OR, 3.97; CI, 1.96-8.06), but also were less certain about their treatment preference (OR, 0.57; CI, 0.41-0.8), had greater prostate cancer anxiety (OR, 1.22; CI, 1.003-1.48), and preferred a shared treatment decision (OR, 2.34; CI, 1.37-3.99). Similarly, men preferring NP (vs. AT) were less certain about treatment preference, preferred a shared decision, and had greater knowledge.
conclusionsAlthough a substantial proportion of men preferred AS, this was associated with anxiety and uncertainty, suggesting that this may be a difficult choice. IMPACT: Increasing the appropriate use of AS for low-risk prostate cancer will require additional reassurance and information, and reaching men almost immediately after diagnosis while the decision-making is ongoing. Cancer Epidemiol Biomarkers Prev; 25(8); 1240-50. ©2016 AACR.
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