Evidence map›Paper›PMID 27256298›Full record

ArticleEuropean journal of nutrition2017

Relationship of equol production between children aged 5-7 years and their mothers.

Keiko Wada, Tomomi Ueno, Shigeto Uchiyama, Yasuhiro Abiru, Michiko Tsuji, Kie Konishi, Fumi Mizuta, Yuko Goto, Takashi Tamura, Makoto Shiraki and 2 more

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In one paragraph

Article in European journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Keiko WadaDepartment of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan. dr_keiko@gifu-u.ac.jp.
Tomomi UenoSaga Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd., Saga, Japan.
Shigeto UchiyamaSaga Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd., Saga, Japan.
Yasuhiro AbiruSaga Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd., Saga, Japan.
Michiko TsujiDepartment of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Kie KonishiDepartment of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Fumi MizutaDepartment of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Yuko GotoDepartment of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Takashi TamuraDepartment of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Makoto ShirakiIwasa Maternity, Gifu, Japan.
Shinichi IwasaIwasa Maternity, Gifu, Japan.
Chisato NagataDepartment of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Gifu University · JPOtsuka (Japan) · JPImmunology Research Institute in Gifu · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe factors responsible for the production of isoflavone metabolites have not yet been identified. We aimed to examine the relationships of equol production between mother and child in a birth cohort in Japan.

methodsSubjects were a part of the participants in a longitudinal study on pregnant women and their offspring. When children were 5-7 years old, mothers and children were asked to reply to a questionnaire on lifestyles and a 3-day child's dietary record. Mothers and children were given a bar-shaped soy snack (Soyjoy

resultsEquol producers were 35.5 % among mothers and 13.8 % among children. Equol producer status of a child was neither associated with dietary intake nor with urinary levels of daidzein and genistein. After multiple adjustments for potential confounders, the estimated relative risk of equol producer was 2.75 (95 % confidence interval 1.00, 7.52) among children whose mother was an equol producer, compared with children whose mother was a non-producer.

conclusionChild's equol production was associated with the mother's equol producer status. The effects of maternal factors on child's equol production should be studied further.

Indexed as

Child Nutritional Physiological PhenomenaDietMaternal Nutritional Physiological PhenomenaAdultChildChild, PreschoolDiet RecordsEquolFemaleFollow-Up StudiesGenisteinHumansIsoflavonesJapanLife StyleLimit of DetectiondaidzeinEquolGenisteinIsoflavonesDietEpidemiologyEquolIsoflavonesMother–childSoy

Identifiers

PMID27256298
OpenAlexW2416906171

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.