ReviewNature reviews. Cardiology2016
Acute coronary syndromes in women and men.
Review in Nature reviews. Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cardiovascular disease risk reduction interventions for indigenous women: an umbrella review.Health promotion international · 2026Pooled it
- Sex differences in secondary preventive follow-up after coronary heart events.BMC cardiovascular disorders · 2023Trial
- Sex- and race/ethnic differences in short- and long-term mortality after hospitalization for incident acute myocardial infarction.American heart journal plus : cardiology research and practice · 2026Article
- Yorga Moorditj Koort: Aboriginal and Torres Strait Islander women's perspectives about heart health on Noongar Boodjar.Health promotion international · 2026Article
- Circadian troponin dynamics reveal sex-specific signals for acute coronary syndrome evaluation.Internal and emergency medicine · 2026Article
- Impact of sex differences on revascularization and long-term clinical outcomes in patients with non-ST-elevation myocardial infarction: a multicentre study from China.Scientific reports · 2026Article
- Sex differences in the presentation and management of acute coronary syndrome patients: Insights from the FORCE-ACS registry.International journal of cardiology. Heart & vasculature · 2026Article
- The Triglyceride-Glucose Index is associated with hospital and Intensive Care Unit Mortality in critically ill patients with Acute Coronary Syndrome.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2026Article
- Sex-based differences in biomarker trajectories in acute coronary syndrome patients from the BIOMArCS study.Scientific reports · 2025Article
- Article
- Sex and Gender-Based Differences in Outcomes of Cardiac Rehabilitation Following Acute Myocardial Infarction.Current atherosclerosis reports · 2025Review
- Addressing Sex Disparities in Coronary Revascularization among Dialysis Patients: A Call for Equity and Precision.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Intersectionality of inequalities in revascularization and outcomes for acute coronary syndrome in England: nationwide linked cohort study.European heart journal. Quality of care & clinical outcomes · 2025Article
- Sex-specific molecular drivers of cardiac fibrosis in aging hearts.GeroScience · 2025Article
- Antithrombotic drugs for acute coronary syndromes in women: sex-adjusted treatment and female representation in randomised clinical trials. A clinical consensus statement of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) and the ESC Working Group on Thrombosis.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025Article
- Sex differences in outcomes in patients with acute myocardial infarction.BMC cardiovascular disorders · 2025Article
- Cardiovascular Risk Factors and Diseases and Awareness of Related Burden in Women: Results of a Survey in Italian Pharmacies.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- Relationship between symptoms, sociodemographic factors, and general practice help-seeking in 10 904 adults aged 50 and over.European journal of public health · 2025Article
- Age- and sex-specific differences in myocardial sympathetic tone and left ventricular remodeling following myocardial injury.Biology of sex differences · 2025Article
- Circulating mitochondrial biomarkers in acute coronary syndrome.Frontiers in medicine · 2025Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Evidence of sex-related disparities in the care and outcomes of patients with acute coronary syndrome (ACS) emerged >30 years ago, and yet the mechanisms behind these sex-specific differences remain unclear. In this Review, we discuss the current literature on differences between women and men in the clinical presentation, pathophysiology, evaluation, management, and outcomes of ACS. Although the symptoms of ACS and the benefits of therapy generally overlap between women and men, women continue to receive less-aggressive invasive and pharmacological therapy than men. In addition, young women in particular have worse short-term and long-term outcomes than men. To understand better the mechanisms behind these continued disparities, we have identified areas of future research that need to be urgently addressed in fields that range from clinical evaluation and management, to increasing representation of women in research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.