Evidence map›Paper›PMID 27255971›Full record

ArticleCellular and molecular neurobiology2017

Caffeoylquinic Acid Derivatives Protect SH-SY5Y Neuroblastoma Cells from Hydrogen Peroxide-Induced Injury Through Modulating Oxidative Status.

Xiao-Wen Jiang, Jun-Peng Bai, Qiao Zhang, Xiao-Long Hu, Xing Tian, Jun Zhu, Jia Liu, Wei-Hong Meng, Qing-Chun Zhao

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  6. Nutritional Metabolites of Red Pigmented Lettuce (Foods (Basel, Switzerland) · 2021
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  7. Polyphenolic Extracts from Spent Coffee Grounds Prevent HMolecules (Basel, Switzerland) · 2021
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  8. Article
  9. Article
  10. Neuroprotective Effects of 7-Geranyloxycinnamic Acid fromMolecules (Basel, Switzerland) · 2020
    Article
  11. Review
  12. Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  13. Article
  14. Nutrients · 2018
    Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiao-Wen JiangDepartment of Pharmacy, General Hospital of Shenyang Military Area Command, Shenyang, 110840, China.
Jun-Peng BaiDepartment of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Qiao ZhangDepartment of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Xiao-Long HuDepartment of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Xing TianDepartment of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Jun ZhuDepartment of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Jia LiuDepartment of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Wei-Hong MengDepartment of Pharmacy, General Hospital of Shenyang Military Area Command, Shenyang, 110840, China.
Qing-Chun ZhaoDepartment of Pharmacy, General Hospital of Shenyang Military Area Command, Shenyang, 110840, China. zhaoqingchun1967@163.com.
Shenyang Pharmaceutical University · CNGeneral Hospital of Shenyang Military Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress has been confirmed as a contribution to the pathogenesis and pathophysiology of many neurological disorders such as Alzheimer's disease and Parkinson's disease. Caffeoylquinic acids (CQAs) are considered to have anti-oxidative stress ability in a previous study, but the structure-activity relationships (SARs) of CQAs in neuroprotective effects are still unclear. In the present study, we primarily expound the SARs of CQAs in counteracting H

Indexed as

ApoptosisCell Line, TumorExtracellular Signal-Regulated MAP KinasesGlutathione PeroxidaseHumansHydrogen PeroxideMalondialdehydeMembrane Potential, MitochondrialNeuroblastomaNeuroprotectionNeuroprotective AgentsOxidative Stressp38 Mitogen-Activated Protein KinasesPhosphorylationProto-Oncogene Proteins c-aktQuinic Acid4,5-o-dicaffeoylquinic acid methyl estercaffeoylquinic acidExtracellular Signal-Regulated MAP KinasesGlutathione PeroxidaseHydrogen PeroxideMalondialdehydeNeuroprotective Agentsp38 Mitogen-Activated Protein KinasesProto-Oncogene Proteins c-aktQuinic AcidSuperoxide DismutaseCaffeoylquinic acidMDCQANeuroprotectionROSSH-SY5Y

Identifiers

PMID27255971
PMCPMC11482068
OpenAlexW4240482978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.