Evidence map›Paper›PMID 27255830›Full record

ArticleJournal of hospital medicine2016

Medications associated with geriatric syndromes and their prevalence in older hospitalized adults discharged to skilled nursing facilities.

Avantika A Saraf, Alec W Petersen, Sandra F Simmons, John F Schnelle, Susan P Bell, Sunil Kripalani, Amy P Myers, Amanda S Mixon, Emily A Long, J Mary Lou Jacobsen and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of hospital medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 5 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 5 syntheses or guidelines pooled it, 91 citations in OpenAlex.

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  19. Sociodemographic and Health-Related Factors Influencing Drug Intake among the Elderly Population.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Avantika A SarafCenter for Quality Aging, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Alec W PetersenSchool of Medicine, Vanderbilt University, Nashville, Tennessee.
Sandra F SimmonsCenter for Quality Aging, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
John F SchnelleCenter for Quality Aging, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Susan P BellCenter for Quality Aging, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Sunil KripalaniSection of Hospital Medicine, Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Amy P MyersDepartment of Pharmaceutical Services, Vanderbilt University Medical Center, Nashville, Tennessee.
Amanda S MixonGeriatric Research, Education and Clinical Center, VA Tennessee Valley Healthcare System, Nashville, Tennessee.
Emily A LongCenter for Quality Aging, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
J Mary Lou JacobsenCenter for Quality Aging, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Eduard E VasilevskisCenter for Quality Aging, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. ed.vasilevskis@vanderbilt.edu.
Vanderbilt University Medical Center · USGeriatric Research Education and Clinical Center · USVanderbilt University · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Predicting Acute Brain Dysfunction in Older Patients: A Quality Improvement ToolK23AG040157 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VASILEVSKIS, EDUARD E · 2011 to 2015
$609k
Longitudinal Hemodynamic and Vascular Changes associated with FrailtyK23AG048347 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BELL, SUSAN POTTER · 2015 to 2016
$345k
NCATS NIH HHS UL1 TR000445NIA NIH HHS K23 AG040157NIA NIH HHS K23 AG048347
6 · The paper itself

Abstract

backgroundMore than half of the hospitalized older adults discharged to skilled nursing facilities (SNFs) have more than 3 geriatric syndromes. Pharmacotherapy may be contributing to geriatric syndromes in this population.

objectivesDevelop a list of medications associated with geriatric syndromes and describe their prevalence in patients discharged from acute care to SNFs.

designLiterature review and multidisciplinary expert panel discussion, followed by cross-sectional analysis.

settingAcademic medical center in the United States

participantsOne hundred fifty-four hospitalized Medicare beneficiaries discharged to SNFs. MEASUREMENTS: Development of a list of medications that are associated with 6 geriatric syndromes. Prevalence of the medications associated with geriatric syndromes was examined in the hospital discharge sample.

resultsA list of 513 medications was developed as potentially contributing to 6 geriatric syndromes: cognitive impairment, delirium, falls, reduced appetite or weight loss, urinary incontinence, and depression. Medications included 18 categories. Antiepileptics were associated with all syndromes, whereas antipsychotics, antidepressants, antiparkinsonism, and opioid agonists were associated with 5 geriatric syndromes. In the prevalence sample, patients were discharged to SNFs with an overall average of 14.0 (±4.7) medications, including an average of 5.9 (±2.2) medications that could contribute to geriatric syndromes, with falls having the most associated medications at discharge at 5.5 (±2.2).

conclusionsMany commonly prescribed medications are associated with geriatric syndromes. Over 40% of all medications ordered upon discharge to SNFs were associated with geriatric syndromes and could be contributing to the high prevalence of geriatric syndromes experienced by this population. Journal of Hospital Medicine 2016;11:694-700. © 2016 Society of Hospital Medicine.

Indexed as

Geriatric AssessmentPolypharmacySkilled Nursing FacilitiesAgedCross-Sectional StudiesFemaleHumansMalePatient DischargePrevalenceUnited States

Identifiers

PMID27255830
PMCPMC5048583
OpenAlexW2411951963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.