Evidence map›Paper›PMID 27255705›Full record

ArticleCerebellum (London, England)2017

Cerebellar Changes in Guinea Pig Offspring Following Suppression of Neurosteroid Synthesis During Late Gestation.

Angela L Cumberland, Hannah K Palliser, David W Walker, Jonathan J Hirst

Abstract read
PubMed Publisher
In one paragraph

Article in Cerebellum (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Neurosteroids and early-life programming: An updated perspective.Current opinion in endocrine and metabolic research · 2022
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Angela L CumberlandSchool of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, 2308, New South Wales, Australia. Angela.Cumberland@uon.edu.au.
Hannah K PalliserSchool of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, 2308, New South Wales, Australia.
David W WalkerHudson Institute of Medical Research, Clayton, 3168, Victoria, Australia.
Jonathan J HirstSchool of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, 2308, New South Wales, Australia.
University of Newcastle Australia · AUHudson Institute of Medical Research · AUHunter Medical Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated gestational concentrations of allopregnanolone are essential for the development and neuroprotection of the foetal brain. Preterm birth deprives the foetus of these high levels of allopregnanolone, which may contribute to the associated adverse effects on cerebellar development. Preterm birth alters expression of GABA

Indexed as

3-Oxo-5-alpha-Steroid 4-DehydrogenaseAnimalsAnimals, NewbornAstrocytesBlotting, WesternCerebellumFemaleFinasterideGuinea PigsImmunohistochemistryMaleModels, AnimalMyelin SheathPregnancyPregnancy ComplicationsPregnanolone3-Oxo-5-alpha-Steroid 4-DehydrogenaseFinasteridePregnanoloneReceptors, GABA-ARNA, MessengerAllopregnanoloneAstrocyteCerebellumFinasterideGABAA receptor

Identifiers

PMID27255705
OpenAlexW2413006896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.