ArticleJournal of biomedical materials research. Part B, Applied biomaterials2017
Comparison of shape memory polymer foam versus bare metal coil treatments in an in vivo porcine sidewall aneurysm model.
Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 58 citations in OpenAlex.
- Evolution of Sac Filling Techniques and Concepts in Endovascular Treatment of Abdominal Aortic Aneurysm: A Narrative Review.Journal of cardiovascular development and disease · 2026Review
- Gold Nanorods as Effective Modulators of Shape Memory Behavior in Physiological Conditions of PLA/PEG Blends.ACS nanoscience Au · 2026Article
- Advanced Design Concepts for Shape-Memory Polymers in Biomedical Applications and Soft Robotics.Polymers · 2026Review
- Single-institution experience with Shape medical polymer sponge embolization as adjunct therapy for rapid aortic remodeling in the multi-modal management of complex persistent large false lumens following aortic dissection.Journal of vascular surgery cases and innovative techniques · 2025Article
- CFD investigations of a shape-memory polymer foam-based endovascular embolization device for the treatment of intracranial aneurysms.Biomechanics and modeling in mechanobiology · 2025Article
- CFD investigations of a shape-memory polymer foam-based endovascular embolization device for the treatment of intracranial aneurysms.Research square · 2024Article
- A novel self-expanding shape memory polymer coil for intracranial aneurysm embolization: 1 year follow-up in Chile.Journal of neurointerventional surgery · 2023Article
- Feasibility of aortic aneurysm sac embolization using a novel shape memory polymer embolic device.European radiology experimental · 2023Article
- Sterilization effects on poly(glycerol dodecanedioate): A biodegradable shape memory elastomer for biomedical applications.Journal of biomedical materials research. Part B, Applied biomaterials · 2023Article
- Embolic Agents: Vascular Plugs.Seminars in interventional radiology · 2022Review
- Image-Based Evaluation of In Vivo Degradation for Shape-Memory Polymer Polyurethane Foam.Polymers · 2022Article
- Macrophage activation in response to shape memory polymer foam-coated aneurysm occlusion devices.Journal of biomedical materials research. Part B, Applied biomaterials · 2022Article
- Shape Memory Polymer-Based Endovascular Devices: Design Criteria and Future Perspective.Polymers · 2022Review
- Article
- Biobased polyurethanes for biomedical applications.Bioactive materials · 2021Review
- Shape Memory Polymer Foams Synthesized Using Glycerol and Hexanetriol for Enhanced Degradation Resistance.Polymers · 2020Article
- Micro-CT and histopathology methods to assess host response of aneurysms treated with shape memory polymer foam-coated coils versus bare metal coil occlusion devices.Journal of biomedical materials research. Part B, Applied biomaterials · 2020Article
- Microscopic Assessment of Healing and Effectiveness of a Foam-Based Peripheral Occlusion Device.ACS biomaterials science & engineering · 2020Article
- Emerging Embolic Agents in Endovascular Embolization: An Overview.Progress in biomedical engineering (Bristol, England) · 2020Article
- Pulsatile Flow-Induced Fatigue-Resistant Photopolymerizable Hydrogels for the Treatment of Intracranial Aneurysms.Frontiers in bioengineering and biotechnology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
The endovascular delivery of platinum alloy bare metal coils has been widely adapted to treat intracranial aneurysms. Despite the widespread clinical use of this technique, numerous suboptimal outcomes are possible. These may include chronic inflammation, low volume filling, coil compaction, and recanalization, all of which can lead to aneurysm recurrence, need for retreatment, and/or potential rupture. This study evaluates a treatment alternative in which polyurethane shape memory polymer (SMP) foam is used as an embolic aneurysm filler. The performance of this treatment method was compared to that of bare metal coils in a head-to-head in vivo study utilizing a porcine vein pouch aneurysm model. After 90 and 180 days post-treatment, gross and histological observations were used to assess aneurysm healing. At 90 days, the foam-treated aneurysms were at an advanced stage of healing compared to the coil-treated aneurysms and showed no signs of chronic inflammation. At 180 days, the foam-treated aneurysms exhibited an 89-93% reduction in cross-sectional area; whereas coiled aneurysms displayed an 18-34% area reduction. The superior healing in the foam-treated aneurysms at earlier stages suggests that SMP foam may be a viable alternative to current treatment methods. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1892-1905, 2017.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.