Evidence map›Paper›PMID 27255574›Full record

ArticleACS applied materials & interfaces2016

Development of Multifunctional Fluorescent-Magnetic Nanoprobes for Selective Capturing and Multicolor Imaging of Heterogeneous Circulating Tumor Cells.

Avijit Pramanik, Aruna Vangara, Bhanu Priya Viraka Nellore, Sudarson Sekhar Sinha, Suhash Reddy Chavva, Stacy Jones, Paresh Chandra Ray

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Avijit PramanikDepartment of Chemistry and Biochemistry, Jackson State University , Jackson, Mississippi 39217, United States.
Aruna VangaraDepartment of Chemistry and Biochemistry, Jackson State University , Jackson, Mississippi 39217, United States.
Bhanu Priya Viraka NelloreDepartment of Chemistry and Biochemistry, Jackson State University , Jackson, Mississippi 39217, United States.
Sudarson Sekhar SinhaDepartment of Chemistry and Biochemistry, Jackson State University , Jackson, Mississippi 39217, United States.
Suhash Reddy ChavvaDepartment of Chemistry and Biochemistry, Jackson State University , Jackson, Mississippi 39217, United States.
Stacy JonesDepartment of Chemistry and Biochemistry, Jackson State University , Jackson, Mississippi 39217, United States.
Paresh Chandra RayDepartment of Chemistry and Biochemistry, Jackson State University , Jackson, Mississippi 39217, United States.
Jackson State University · US

Funding

RCMI-Center for Environmental HealthG12MD007581 · NIMHD · JACKSON STATE UNIVERSITY · PI TCHOUNWOU, PAUL B. · 2012 to 2017
$11.2M
NIMHD NIH HHS G12 MD007581
6 · The paper itself

Abstract

Circulating tumor cells (CTC) are highly heterogeneous in nature due to epithelial-mesenchymal transition (EMT), which is the major obstacle for CTC analysis via "liquid biopsy". This article reports the development of a new class of multifunctional fluorescent-magnetic multicolor nanoprobes for targeted capturing and accurate identification of heterogeneous CTC. A facile design approach for the synthesis and characterization of bioconjugated multifunctonal nanoprobes that exhibit excellent magnetic properties and emit very bright and photostable multicolor fluorescence at red, green, and blue under 380 nm excitation is reported. Experimental data presented show that the multifunctional multicolor nanoprobes can be used for targeted capture and multicolor fluorescence mapping of heterogeneous CTC and can distinguish targeted CTC from nontargeted cells.

Indexed as

MagneticsBiomarkers, TumorCell CountCell Line, TumorDiagnostic ImagingFluorescent DyesHumansNanotechnologyNeoplastic Cells, CirculatingBiomarkers, TumorFluorescent Dyesheterogeneous circulating tumor cell capturingmapping of epithelial, mesenchymal, and stem cells simultaneouslymulticolor fluorescence nanodotsmultifunctional fluorescent−magnetic nanoprobes

Identifiers

PMID27255574
PMCPMC4957586
OpenAlexW2411564911

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.