Evidence map›Paper›PMID 27255373›Full record

ArticleBMC cardiovascular disorders2016

Pharmacological treatment of hypertension and hyperlipidemia in Izhevsk, Russia.

Marta Cybulsky, Sarah Cook, Anna V Kontsevaya, Maxim Vasiljev, David A Leon

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Marta CybulskyMcGill University, Montréal, Canada.
Sarah CookDepartment of Non Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. sarah.cook@lshtm.ac.uk.
Anna V KontsevayaNational Research Centre for Preventive Medicine, Moscow, Russia.
Maxim VasiljevIzhevsk State Medical Academy, Izhevsk, Russia.
David A LeonDepartment of Non Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
London School of Hygiene & Tropical Medicine · GBIzhevsk State Medical Academy · RUMcGill University · CANational Research Center for Preventive Medicine · RU

Funding

Wellcome Trust 078557
6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) is the leading cause of death in Russia. Hypertension and hyperlipidemia are important risk factors for CVD that are modifiable by pharmacological treatment and life-style changes. We aimed to characterize the extent of the problem in a typical Russian city by examining the prevalence, treatment and control rates of hypertension and hyperlipidemia and investigating whether the specific pharmacological regimes used were comparable with guidelines from a country with much lower CVD rates.

methodsThe Izhevsk Family Study II included a cross-sectional survey of a population sample of 1068 men, aged 25-60 years conducted in Izhevsk, Russia (2008-2009). Blood pressure and total cholesterol were measured and self-reported medication use was recorded by a clinician. We compared drug treatments with the Russian and Canadian treatment guidelines for hypertension and hyperlipidemia.

resultsThe prevalence of hypertension was 61 % (age-standardised prevalence 51 %), with 66 % of those with hypertension aware of their diagnosis and 50 % of those aware taking treatment. 17 % of those taking treatment achieved blood pressure control. The majority (59 %) of those taking treatment were not doing so regularly. Prevalence of hyperlipidemia was 45 % (age-standardised prevalence 40 %), however less than 2 % of those with hyperlipidemia were taking any treatment. Types of lipid-lowering and anti-hypertensive medications prescribed were broadly in line with Russian and Canadian guidelines.

conclusionThe prevalence of hypertension and hyperlipidemia is high in Izhevsk while the proportion of those treated and attaining treatment targets is very low. Prescribed medications were concurrent with those in Canada, but adherence is a major issue.

Indexed as

AdultAntihypertensive AgentsBiomarkersBlood PressureCanadaCardiovascular DiseasesCholesterolCross-Sectional StudiesGuideline AdherenceHealthcare DisparitiesHumansHyperlipidemiasHypertensionHypolipidemic AgentsMaleMedication AdherenceAntihypertensive AgentsBiomarkersCholesterolHypolipidemic AgentsAnticholesterolemic agentsAntihypertensive agentsHyperlipidemiaHypertensionPrevalenceRussiaTreatment

Identifiers

PMID27255373
PMCPMC4891885
OpenAlexW2414333094

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.