ReviewJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2016
The Road to Reproducibility in Animal Research.
Review in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Inadequate awareness of adherence to ARRIVE guidelines, regarding reporting quality of hernia models repaired with meshes: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2022Pooled it
- Pooled it
- Impaired reproduction after exposure to ADHD drugs: Systematic review of animal studies.The International journal of risk & safety in medicine · 2017Pooled it
- Commentary: Comparison of radiological interpretation made by veterinary radiologists and state-of-the-art commercial AI software for canine and feline radiographic studies.Frontiers in veterinary science · 2025Article
- Reporting quality of animal research in journals that published the ARRIVE 1.0 or ARRIVE 2.0 guidelines: a cross-sectional analysis of 943 studies.Cardiovascular diagnosis and therapy · 2024Article
- Still to ARRIVE at adequate reporting of orthodontic studies involving animal models.European journal of orthodontics · 2024Article
- Review
- Bioethical, Reproducibility, and Translational Challenges of Animal Models.ILAR journal · 2021Review
- Common methodological issues and suggested solutions in bone research.Osteoporosis and sarcopenia · 2020Review
- Validation of alternative behavioral observation methods in young broiler chickens.Poultry science · 2019Article
- Scoping review on interventions to improve adherence to reporting guidelines in health research.BMJ open · 2019Article
- Dietary Pyrophosphate Modulates Calcification in a Mouse Model of Pseudoxanthoma Elasticum: Implication for Treatment of Patients.The Journal of investigative dermatology · 2019Article
- Vibration in mice: A review of comparative effects and use in translational research.Animal models and experimental medicine · 2018Review
- Article
- The price of progress: Funding and financing Alzheimer's disease drug development.Alzheimer's & dementia (New York, N. Y.) · 2018Article
- Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments.Frontiers in aging neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Reproducibility of research findings is the hallmark of scientific advance. However, the recently noted lack of reproducibility and transparency of published research using animal models of human biology and disease has alarmed funders, scientists, and the public. Improved reporting of methodology and better use of statistical tools are needed to enhance the quality and utility of published research. Reporting guidelines like Animal Research: Reporting In Vivo Experiments (ARRIVE) have been devised to achieve these goals, but most biomedical research journals, including the JBMR, have not been able to obtain high compliance. Cooperative efforts among authors, reviewers and editors-empowered by increased awareness of their responsibilities, and enabled by user-friendly guidelines-are needed to solve this problem. © 2016 American Society for Bone and Mineral Research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.