ArticleBMC biotechnology2016
Fatty acid and metabolomic profiling approaches differentiate heterotrophic and mixotrophic culture conditions in a microalgal food supplement 'Euglena'.
Article in BMC biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 48 citations in OpenAlex.
- Peculiar proteome of dark-cultivated Euglena gracilis.Scientific reports · 2025Article
- Metabolomic Insights into the Adaptations and Biotechnological Potential ofPlants (Basel, Switzerland) · 2025Article
- Glycosylated proteins in the protozoan alga Euglena gracilis: a proteomic approach.FEMS microbiology letters · 2023Article
- Microalgal photoautotrophic growth induces pH decrease in the aquatic environment by acidic metabolites secretion.Biotechnology for biofuels and bioproducts · 2022Article
- Heterotrophic Cultivation ofMolecules (Basel, Switzerland) · 2022Article
- Evaluation ofFrontiers in bioengineering and biotechnology · 2022Article
- Anti-Inflammatory Activities ofMicroorganisms · 2021Article
- Metabolomic Study of Heterotrophically GrownMolecules (Basel, Switzerland) · 2021Article
- Mass Spectrometry-Based Metabolomics Combined with Quantitative Analysis of the Microalgal Diatom (Marine drugs · 2020Article
- Pre-concentration of microalgaBiotechnology for biofuels · 2020Article
- Transcriptome, proteome and draft genome of Euglena gracilis.BMC biology · 2019Article
- Article
- Euglena gracilis growth and cell composition under different temperature, light and trophic conditions.PloS one · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicroalgae have been recognized as a good food source of natural biologically active ingredients. Among them, the green microalga Euglena is a very promising food and nutritional supplements, providing high value-added poly-unsaturated fatty acids, paramylon and proteins. Different culture conditions could affect the chemical composition and food quality of microalgal cells. However, little information is available for distinguishing the different cellular changes especially the active ingredients including poly-saturated fatty acids and other metabolites under different culture conditions, such as light and dark.
resultsIn this study, together with fatty acid profiling, we applied a gas chromatography-mass spectrometry (GC-MS)-based metabolomics to differentiate hetrotrophic and mixotrophic culture conditions.
conclusionsThis study suggests metabolomics can shed light on understanding metabolomic changes under different culture conditions and provides a theoretical basis for industrial applications of microalgae, as food with better high-quality active ingredients.
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