ReviewCurrent opinion in HIV and AIDS2016
Reducing rates of preventable HIV/AIDS-associated mortality among people living with HIV who inject drugs.
Review in Current opinion in HIV and AIDS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Promoting Healthy Aging Through Mindfulness and Yoga: A Systematic Review of Interventions for People Living with HIV Who Use Drugs or Who Have a History of Substance Use.International journal of environmental research and public health · 2025Pooled it
- Improving Post-Release Care Engagement for People Living with HIV Involved in the Criminal Justice System: A Systematic Review.AIDS and behavior · 2022Pooled it
- All-Cause and Cause-Specific Mortality Among People Using Extramedical Opioids: A Systematic Review and Meta-analysis.JAMA psychiatry · 2020Pooled it
- Clinical effects of adjunctive spleen- and kidney-invigorating Chinese herbal therapy combined with highly active antiretroviral treatment on immune recovery and nutritional status in people living with HIV.Malawi medical journal : the journal of Medical Association of Malawi · 2026Trial
- Resilience and Its Determinants Among Adolescents and Young Adults with Perinatally Acquired HIV Enrolled in a Peer-Led Mentorship Program in India.AIDS and behavior · 2026Article
- Cardiovascular risk profiles in people living with HIV taking antiretroviral therapy in rural Lesotho: Findings from the PRECARIF study.Southern African journal of HIV medicine · 2026Article
- Perceived HIV-related stigma: disparities between an Infectious Diseases Unit and other hospital departments.AIDS research and therapy · 2025Article
- Rapid initiation of antiretrovirals at a syringe services program for people with HIV who inject drugs.Annals of medicine · 2025Article
- Joinpoint regression and age period cohort analysis of global and Chinese HIV incidence trends from 1990 to 2021.Scientific reports · 2025Article
- Prevalence and Associated Factors of Non-Alcoholic Fatty Liver Disease in People Living with HIV-1.Current HIV research · 2025Article
- Applying population-specific incidence prevalence ratio benchmarks to monitor the Australian HIV epidemic: an epidemiological analysis.Journal of the International AIDS Society · 2024Article
- Past-Year HIV Testing, Current Antiretroviral Therapy Use, and Participation in Services for People Who Inject Drugs.AIDS and behavior · 2024Article
- Mortality among HIV-Positive and HIV-Negative People Who Inject Drugs in Mizoram, Northeast India: A Repeated Cross-Sectional Study (2007-2021).International journal of environmental research and public health · 2024Article
- Long-acting HIV Treatments: Study Design, Logistics, and Access.Open forum infectious diseases · 2024Review
- Evolving AIDS- and non-AIDS Mortality and Predictors in the PISCIS Cohort of People Living With HIV in Catalonia and the Balearic Islands (Spain), 1998-2020.Open forum infectious diseases · 2024Article
- Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016-17.Drug and alcohol dependence · 2024Article
- Integrating long-acting injectable treatment to improve medication adherence among persons living with HIV and opioid use disorder: study protocol.Addiction science & clinical practice · 2023Article
- Contribution of alcohol use in HIV/hepatitis C virus co-infection to all-cause and cause-specific mortality: A collaboration of cohort studies.Journal of viral hepatitis · 2023Article
- HIV treatment, antiretroviral adherence and AIDS mortality in people who inject drugs: a scoping review.European journal of public health · 2023Article
- From crisis to crisis: impacts of the COVID-19 pandemic on people living with HIV and HIV/AIDS service organizations in Indiana.BMC health services research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
purpose of reviewThe modern antiretroviral therapy (ART) era has seen substantial reductions in mortality among people living with HIV. However, HIV-positive people who inject drugs (PWIDs) continue to experience high rates of suboptimal HIV-related outcomes. We review recent findings regarding factors contributing to premature and preventable mortality among HIV-positive PWID, and describe the promise of interventions to improve survival in this group. RECENT
findingsThe current leading causes of death among HIV-positive PWID are HIV/AIDS-related causes, overdose, and liver-related causes, including infection with hepatitis C virus. Elevated mortality levels in this population are driven by social-structural barriers to ART access and adherence, particularly criminalization and stigmatization of drug use. In contexts where opioid substitution therapy and ART adherence support programs are widely accessible, evidence highlights comparable levels of survival among HIV-positive PWID and people living with HIV who do not inject drugs. SUMMARY: The life-saving benefits of ART can be realized among HIV-positive PWID when it is paired with strategies that address barriers to evidence-based medical care. Joint administration of ART and opioid substitution therapy, as well as repeal of punitive laws that criminalize drug users, are urgently needed to reduce HIV and injection-related mortality among PWID.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.