Evidence map›Paper›PMID 27253449›Full record

ArticleNeuron2016

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia.

Weixing Shen, Joshua L Plotkin, Veronica Francardo, Wai Kin D Ko, Zhong Xie, Qin Li, Tim Fieblinger, Jürgen Wess, Richard R Neubig, Craig W Lindsley and 5 more

Abstract readPublished Erratum
In one paragraph

Article in Neuron, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Levodopa treatment: impacts and mechanisms throughout Parkinson's disease progression.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Dopaminergic modulation of striatal function and Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2019
    Review
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Weixing Shen
Joshua L Plotkin
Veronica Francardo
Wai Kin D Ko
Zhong Xie
Qin Li
Tim Fieblinger
Jürgen Wess
Richard R Neubig
Craig W Lindsley
P Jeffrey Conn
Paul Greengard
Erwan Bezard
M Angela Cenci
D James Surmeier

Funding

Muscarinic receptor activators as novel antipsychotic agentsR01MH073676 · NIMH · VANDERBILT UNIVERSITY · PI Jerri Michelle Rook · 2006 to 2026
$9.3M
Udall Parkinson's Disease Center at Emory University: Circuitry to TherapyP50NS071669 · NINDS · EMORY UNIVERSITY · PI WICHMANN, THOMAS · 2010 to 2015
$6.8M
NIMH NIH HHS R01 MH073676NINDS NIH HHS P50 NS071669
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID27253449
PMCPMC6055921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.