ArticlePloS one2016
Quality of Life and Mortality of Long-Term Colorectal Cancer Survivors in the Seattle Colorectal Cancer Family Registry.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- The effect of ginseng extract on fatigue in cancer survivors: a randomized double-blind clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Trial
- Occupational therapy to improve quality of life for colorectal cancer survivors: a randomized clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Trial
- Predictors of impaired quality of life among colorectal cancer survivors: a cross-sectional study.Journal of patient-reported outcomes · 2025Article
- Health-related quality of life and lifestyle in long-term survivors of colorectal cancer and a matched non-cancer reference group.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Article
- Health-related quality of life trajectories in older adult long-term survivors of colorectal cancer.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Temporal relationship between symptom cluster and quality of life in rectal cancer patients after laparoscopic anus-preserving surgery.Scientific reports · 2024Article
- Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors.Healthcare (Basel, Switzerland) · 2024Article
- Demographic and Clinical Factors Associated With Health-Related Quality-of-Life Profiles Among Prostate Cancer Survivors.JCO oncology practice · 2024Article
- Quality of Life Outcomes in Stage IV Colorectal Cancer.Clinics in colon and rectal surgery · 2024Review
- Article
- The prevalence and risk of symptom and function clusters in colorectal cancer survivors.Journal of cancer survivorship : research and practice · 2022Article
- Anxiety, depression, health-related quality of life, and mortality among colorectal patients: 5-year follow-up.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Observational
- The burden of colorectal cancer survivors in the Netherlands: costs, utilities, and associated patient characteristics.Journal of cancer survivorship : research and practice · 2022Article
- Symptom burden, psychological distress, and health-related quality of life in cancer survivors with pelvic late radiation tissue injuries.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Health-related quality of life among colorectal cancer survivors of diverse sexual orientations.Cancer · 2021Article
- A survey of cancer patients, caregivers, and providers regarding familiarity, importance, and utilization of supportive and integrative oncology services.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Time from Diagnosis and Correlates of Health-Related Quality of Life among Young Adult Colorectal Cancer Survivors.Cancers · 2021Article
- Increases in adipose tissue and muscle function are longitudinally associated with better quality of life in colorectal cancer survivors.Scientific reports · 2021Observational
- Heterogeneity in Quality of Life of Long-Term Colon Cancer Survivors: A Latent Class Analysis of the Population-Based PROFILES Registry.The oncologist · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
BACKGROUND AND
aimBecause most colorectal cancer patients survive beyond five years, understanding quality of life among these long-term survivors is essential to providing comprehensive survivor care. We sought to identify personal characteristics associated with reported quality of life in colorectal cancer survivors, and sub-groups of survivors potentially vulnerable to very low quality of life.
methodsWe assessed quality of life using the Veterans RAND 12-item Health Survey within a population-based sample of 1,021 colorectal cancer survivors in the Seattle Colorectal Cancer Family Registry, approximately 5 years post-diagnosis. In this case-only study, mean physical component summary scores and mental component summary scores were examined with linear regression. To identify survivors with substantially reduced ability to complete daily tasks, logistic regression was used to estimate odds ratios for "very low" summary scores, defined as a score in the lowest decile of the reference US population. All cases were followed for vital status following QoL assessment, and mortality was analyzed with Cox proportional hazards regression.
resultsLower mean physical component summary score was associated with older age, female sex, obesity, smoking, and diabetes or other co-morbidity; lower mean mental component summary score was associated with younger age and female sex. Higher odds of very low physical component summary score was associated with older age, obesity, less education, smoking, co-morbidities, and later stage at diagnosis; smoking was associated with higher odds of very low mental component summary score. A very low physical component score was associated with higher risk of mortality (hazard ratio (95% confidence interval): 3.97 (2.95-5.34)).
conclusionsOur results suggest that identifiable sub-groups of survivors are vulnerable to very low physical components of quality of life, decrements that may represent meaningful impairment in completing everyday tasks and are associated with higher risk of death.
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