ArticleBritish journal of cancer2016
Association between prediagnostic glucose, triglycerides, cholesterol and meningioma, and reverse causality.
Article in British journal of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Brief results of heterotopic xenotransplantation of meningioma into the peritoneum of Wistar rats: an experimental study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026Article
- Association of thyroid disease and intracranial meningiomas: a retrospective analysis with external validation.Frontiers in oncology · 2025Article
- Effect of Different Glucose Levels and Glycation on Meningioma Cell Migration and Invasion.International journal of molecular sciences · 2024Article
- Lifestyle and metabolic factors affect risk for meningioma in women: a prospective population-based study (The Cohort of Norway).Frontiers in oncology · 2024Article
- Role of Mediterranean diet in the development and recurrence of meningiomas: a narrative review.Neurosurgical review · 2023Review
- Incidence and Risk Factors of Vestibular Schwannoma in Korea : A Population-Based Study.Journal of Korean Neurosurgical Society · 2023Article
- The causal relationship between genetically determined telomere length and meningiomas risk.Frontiers in neurology · 2023Article
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- Body mass index, comorbidities, and hormonal factors in relation to meningioma in an ethnically diverse population: the Multiethnic Cohort.Neuro-oncology · 2019Article
- Factors Associated With Meningioma Detected in a Population-Based Sample.Mayo Clinic proceedings · 2019Article
- Mendelian randomization provides support for obesity as a risk factor for meningioma.Scientific reports · 2019Article
- Association of serum lipids and severity of epithelial ovarian cancer: an observational cohort study of 349 Chinese patients.Journal of biomedical research · 2018Article
- Associations between prediagnostic blood glucose levels, diabetes, and glioma.Scientific reports · 2017Article
- Metabolic syndrome in relation to risk of meningioma.Oncotarget · 2017Article
- Diabetes, use of metformin, and the risk of meningioma.PloS one · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundAlthough meningioma is a benign tumour, it may cause significant morbidity. Obesity and diabetes are positively associated with meningioma. To evaluate the potential effects of obesity-related prediagnostic glucose, triglycerides and cholesterol on meningioma and of prediagnostic meningioma on these biomarkers, we conducted a cohort study.
methodsWe identified 41 355 individuals in the Apolipoprotein MOrtality RISk cohort with values for these biomarkers within 15 years before meningioma diagnosis, death, migration or the end of follow-up. We then estimated hazard ratios (HRs) and their interactions with time and age using Cox regression.
resultsMeningioma was diagnosed in 181 women and 115 men whose median follow-up time was 7 years. Fasting serum glucose level was inversely related to meningioma among women (Ptrend=0.0006) but not men (Ptrend=0.24). Prediagnostic diabetes was inversely related to meningioma in both sexes combined (HR=0.45, 95% confidence interval (CI) 0.29-0.71), as was serum cholesterol within the year before diagnosis (HR=0.50, 95% CI 0.34-0.72).
conclusionsParadoxically, hyperglycaemia is inversely associated with meningioma in women. This finding does not necessarily negate the positive role of obesity or diabetes in meningioma development; rather, it may indicate that their effects depend on the stage of development. Furthermore, the prediagnostic tumour may reduce serum cholesterol levels.
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