Evidence map›Paper›PMID 27252935›Full record

ReviewFrontiers in pediatrics2016

Long-term Outcomes of Childhood Onset Nephrotic Syndrome.

Rebecca Hjorten, Zohra Anwar, Kimberly Jean Reidy

Abstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Nephrotic Syndrome: Current Management.Indian journal of pediatrics · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Longitudinal analysis of blood pressure and lipids in childhood nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2024 · on this map
    Observational
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rebecca HjortenPediatrics Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine , Bronx, NY , USA.
Zohra AnwarPediatrics Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine , Bronx, NY , USA.
Kimberly Jean ReidyPediatrics Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine , Bronx, NY , USA.

Funding

DEVELOPMENTAL RENAL AND ELECTROLYTE PHYSIOLOGYT32DK007110 · NIDDK · YESHIVA UNIVERSITY · PI KASKEL, FREDERICK JEFFREY, MELAMED, MICHAL L · 1986 to 2021
$5.6M
RESEARCH TRAINING IN PEDIATRIC NEPHROLOGYT32DK007695 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI DEVARAJAN, PRASAD · 1992 to 2023
$2.2M
NIDDK NIH HHS T32 DK007110NIDDK NIH HHS T32 DK007695
6 · The paper itself

Abstract

There are limited studies on long-term outcomes of childhood onset nephrotic syndrome (NS). A majority of children with NS have steroid-sensitive nephrotic syndrome (SSNS). Steroid-resistant nephrotic syndrome (SRNS) is associated with a high risk of developing end-stage renal disease. Biomarkers and analysis of genetic mutations may provide new information for prognosis in SRNS. Frequently relapsing and steroid-dependent NS is associated with long-term complications, including dyslipidemia, cataracts, osteoporosis and fractures, obesity, impaired growth, and infertility. Long-term complications of SSNS are likely to be under-recognized. There remain many gaps in our knowledge of long-term outcomes of childhood NS, and further study is indicated.

Indexed as

childrenfocal glomerulosclerosisgeneticsminimal-change diseasenephrotic syndromeoutcomespediatric

Identifiers

PMID27252935
PMCPMC4879783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.