ArticleIranian journal of public health2016
Characterization of Staphylococcus aureus Biofilm Formation in Urinary Tract Infection.
Article in Iranian journal of public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- The global prevalence of Daptomycin, Tigecycline, Quinupristin/Dalfopristin, and Linezolid-resistant Staphylococcus aureus and coagulase-negative staphylococci strains: a systematic review and meta-analysis.Antimicrobial resistance and infection control · 2020Pooled it
- Staphylococcus aureus contamination in traditional buffalo milk supply chain in Bangladesh.Tropical animal health and production · 2026Article
- Fabrication of nitrofurantoin-loaded chitosan-silver nanoparticles for the treatment of urinary tract infections.Scientific reports · 2026Article
- Microbial and inflammatory profiling of pressure injuries and urinary tract infections in spinal cord injury: a prospective cohort study.Scientific reports · 2026Article
- Staphylococci: What Has Changed in the Antibiotic Resistance Profile in the Last Decade-Analysis of Strains Isolated from Hospitalised Patients.Pathogens (Basel, Switzerland) · 2025Article
- Biofilm-mediated antimicrobial resistance among meat-borne pathogens in Al-Suwaria, Iraq: A cross-species investigation from retail markets.Veterinary world · 2025Article
- Comparison of chromogenic and cysteine lactose electrolyte deficient agar for identification of uropathogens in Gujarat, India.African journal of laboratory medicine · 2025Article
- Combining Plant Bioactives With Antibiotics for Enhanced Antibiofilm Activity Against UropathogenicAdvances in pharmacological and pharmaceutical sciences · 2025Article
- Unveiling the Genetic Landscape ofInternational journal of microbiology · 2025Article
- Phenotypic and genotypic characterization ofHeliyon · 2024Article
- Antibiotic resistance, biofilm formation, and molecular epidemiology of Staphylococcus aureus in a tertiary hospital in Xiangyang, China.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Lower Urinary Tract Inflammation and Infection: Key Microbiological and Immunological Aspects.Journal of clinical medicine · 2024Review
- The Antibiofilm Effects of Antimony Tin Oxide Nanoparticles against Polymicrobial Biofilms of UropathogenicPharmaceutics · 2023Article
- Isolation of Staphylococcus aureus Urinary Tract Infections at a Community-Based Healthcare Center in Riyadh.Cureus · 2023Article
- Phenotypic and Molecular Detection of Biofilm Formation in Methicillin-ResistantMediterranean journal of hematology and infectious diseases · 2023Article
- Molecular Detection ofArchives of Razi Institute · 2022Article
- Mupirocin-ResistantBioMed research international · 2022Article
- Relationship between Biofilm Formation and Antibiotic Resistance and Adherence Genes inInternational journal of microbiology · 2022Article
- Inducible Clindamycin Resistance and Biofilm Production among Staphylococci Isolated from Tertiary Care Hospitals in Nepal.Infectious disease reports · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to investigate the antibiotic susceptibility pattern as well as the phenotypic and genotypic biofilm formation ability of Staphylococcus aureus isolates from patients with urinary tract infection (UTI).
methodsA total of 39 isolates of S. aureus were collected from patients with UTI. The antibiotic susceptibility patterns of the isolates were determined by the Kirby-Bauer disk-diffusion. We used the Modified Congo red agar (MCRA) and Microtiter plate methods to assess the ability of biofilm formation. All isolates were examined for determination of biofilm related genes, icaA, fnbA, clfA and bap using PCR method.
resultsLinezolid, quinupristin/dalfopristin and chloramphenicol were the most effective agents against S. aureus isolates. Overall, 69.2% of S. aureus isolates were biofilm producers. Resistance to four antibiotics such as nitrofurantoin (71.4% vs. 28.6%, P=0.001), tetracycline (57.7% vs. 42.3%, P=0.028), erythromycin and ciprofloxacin (56% vs. 44%, P=0.017) was higher among biofilm producers than non-biofilm producers. The icaA, fnbA and clfA genes were present in all S. aureus isolates. However, bap gene was not detected in any of the isolates.
conclusionOur findings reinforce the role of biofilm formation in resistance to antimicrobial agents. Trimethoprimsulfamethoxazole and doxycycline may be used as an effective treatment for UTI caused by biofilm producers S. aureus. Our results suggest that biofilm formation is not dependent to just icaA, fnbA, clfA and bap genes harbor in S. aureus strains.
Indexed as
Identifiers
27252918PMC4888176W2402922336What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.