Evidence map›Paper›PMID 27252912›Full record

ArticleIranian journal of public health2016

Predictive Role of Serum Tumor Markers in Diagnosis of Pulmonary Tuberculosis.

Jingjing Ma, Dan Xia, Jing Hu, Rui Fu, Lijun Xu, Ying Zhang, Mengying Zhang, Benhe Li, Jianghua Yang, Yufeng Wen

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Iranian journal of public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jingjing MaDept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China.
Dan XiaDept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China.
Jing HuDept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China.
Rui FuDept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China.
Lijun XuDept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China.
Ying ZhangDept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China.
Mengying ZhangDept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China.
Benhe LiDept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China.
Jianghua YangDept. of Infectious Diseases, Yijishan Hospital, Wuhu City, China.
Yufeng WenDept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China.
Wannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnosis of pulmonary tuberculosis (PTB) is complicated and time-consuming currently. There was association of PTB with serum tumor markers. In this study we aimed to evaluate the predictive role of serum CA125, CA199 and CEA as diagnostic tools for PTB.

methodsThis study was designed as a case-control study with 565 subjects who visited the Yijishan Hospital from Jun to Dec in 2014.This case-control study matched as for age and sex with 113 cases and 452 controls. Serum CA125, CA199 and CEA levels were detected by electrochemiluminescence instrument. The area under the curve (AUC) of the receiver operating characteristic (ROC) curve was performed to evaluate the diagnostic value on PTB.

resultsSerum levels of CA125, CA199 and CEA in PTB patients were significantly higher than those in control group (P<0.001). There was no significantly different of three tumor markers between initial treatment group and retreatment group. The logistic regression analysis showed that CA125 was an impact factor to PTB. The ROC analysis revealed that AUC of CA125 was 0.966 (95%CI: 0.951-0.981), the sensitivity, specificity in serum and cut-off were 95.6%, 85.0% and 10.30 U/ml, respectively.

conclusionThe serum CA125 has potential good diagnostic performance for PTB.

Indexed as

CA125CA199CEACharacteristic curvePulmonary tuberculosisReceiver-operating

Identifiers

PMID27252912
PMCPMC4888170
OpenAlexW2344613635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.