Evidence map›Paper›PMID 27252878›Full record

ArticleOpen heart

Health utility indexes in patients with acute coronary syndromes.

Baris Gencer, Nicolas Rodondi, Reto Auer, David Nanchen, Lorenz Räber, Roland Klingenberg, Mark Pletscher, Peter Jüni, Stephan Windecker, Christian M Matter and 4 more

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Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
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13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  5. Article
  6. Sex differences in quality of life of patients following percutaneous coronary intervention in Vietnam.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  7. Article
  8. Using Published Health Utilities in Cost-Utility Analyses: Discrepancies and Issues in Cardiovascular Disease.Medical decision making : an international journal of the Society for Medical Decision Making · 2021
    Article
  9. Article
  10. Article
  11. EQ-5D in coronary patients: what are they suffering from? Results from the ESC EORP European Survey of Cardiovascular Disease Prevention and Diabetes (EUROASPIRE IV) Registry.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Baris GencerCardiology Division , Geneva University Hospitals, University of Geneva , Geneva , Switzerland.
Nicolas RodondiDepartment of General Internal Medicine , Inselspital, Bern University Hospital, University of Bern , Bern , Switzerland.
Reto AuerDepartment of Community Medicine and Ambulatory Care , University of Lausanne , Lausanne , Switzerland.
David NanchenDepartment of Community Medicine and Ambulatory Care , University of Lausanne , Lausanne , Switzerland.
Lorenz RäberDepartment of Cardiology , Inselspital, Bern University Hospital, University of Bern , Bern , Switzerland.
Roland KlingenbergDepartment of Cardiology , University Heart Center , Zurich , Switzerland.
Mark PletscherWinterthur Institute of Health Economics, Zurich University of Applied Sciences , Winterthur , Switzerland.
Peter JüniInstitute of Primary Health Care, University of Bern, Bern, Switzerland; Applied Health Research Centre (AHRC), Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Toronto, Canada.
Stephan WindeckerDepartment of Cardiology , Inselspital, Bern University Hospital, University of Bern , Bern , Switzerland.
Christian M MatterDepartment of Cardiology , University Heart Center , Zurich , Switzerland.
Thomas F LüscherDepartment of Cardiology , University Heart Center , Zurich , Switzerland.
François MachCardiology Division , Geneva University Hospitals, University of Geneva , Geneva , Switzerland.
Thomas V PernegerDivision of Clinical Epidemiology , University Hospital , Geneva , Switzerland.
François R GirardinMedical Directorate, University Hospital of Geneva, Geneva, Switzerland; Department of Anaesthesiology, Clinical Pharmacology, and Intensive Care Medicine, University Hospitals of Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute coronary syndromes (ACS) have been associated with lower health utilities (HUs) compared with the general population. Given the prognostic improvements after ACS with the implementation of coronary angiography (eg, percutaneous coronary intervention (PCI)), contemporary HU values derived from patient-reported outcomes are needed.

methodsWe analysed data of 1882 patients with ACS 1 year after coronary angiography in a Swiss prospective cohort. We used the EuroQol five-dimensional questionnaire (EQ-5D) and visual analogue scale (VAS) to derive HU indexes. We estimated the effects of clinical factors on HU using a linear regression model and compared the observed HU with the average values of individuals of the same sex and age in the general population.

resultsMean EQ-5D HU 1-year after coronary angiography for ACS was 0.82 (±0.16) and mean VAS was 0.77 (±0.18); 40.9% of participants exhibited the highest utility values. Compared with population controls, the mean EQ-5D HU was similar (expected mean 0.82, p=0.58) in patients with ACS, but the mean VAS was slightly lower (expected mean 0.79, p<0.001). Patients with ACS who are younger than 60 years had lower HU than the general population (<0.001). In patients with ACS, significant differences were found according to the gender, education and employment status, diabetes, obesity, heart failure, recurrent ischaemic or incident bleeding event and participation in cardiac rehabilitation (p<0.01).

conclusionsAt 1 year, patients with ACS with coronary angiography had HU indexes similar to a control population. Subgroup analyses based on patients' characteristics and further disease-specific instruments could provide better sensitivity for detecting smaller variations in health-related quality of life.

Indexed as

Acute coronary syndromeshealth utilitypatient-reported outcomesquality of life

Identifiers

PMID27252878
PMCPMC4885435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.