Evidence map›Paper›PMID 27252592›Full record

ArticleCurrent genomics2016

Nutrigenomics and its Impact on Life Style Associated Metabolic Diseases.

Shalika Rana, Shiv Kumar, Nikita Rathore, Yogendra Padwad, Shashi Bhushana

Open access · bronzeAbstract read
In one paragraph

Article in Current genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  8. Article
  9. Gene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg Debate.International journal of molecular sciences · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shalika RanaDepartment of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176 061 (HP), India;; Academy of Scientific and Innovative Research, CSIR-Institute of Himalayan Bioresource Technology, Palampur176 061 (HP), India.
Shiv KumarPharmacology and Toxicology Lab, Department of Food Nutraceuticals and Quality Control, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176 061 (HP), India;; Academy of Scientific and Innovative Research, CSIR-Institute of Himalayan Bioresource Technology, Palampur176 061 (HP), India.
Nikita RathoreDepartment of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176 061 (HP), India;
Yogendra PadwadPharmacology and Toxicology Lab, Department of Food Nutraceuticals and Quality Control, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176 061 (HP), India;; Academy of Scientific and Innovative Research, CSIR-Institute of Himalayan Bioresource Technology, Palampur176 061 (HP), India.
Shashi BhushanaDepartment of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176 061 (HP), India;; Academy of Scientific and Innovative Research, CSIR-Institute of Himalayan Bioresource Technology, Palampur176 061 (HP), India.
Institute of Himalayan Bioresource Technology · INAcademy of Scientific and Innovative Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-human genome revelation observes the emergence of 'Nutigenomics' as one of the exciting scientific advancement influencing mankind around the world. Food or more precisely 'nutrition' has the major impact in defining the cause-response interaction between nutrient (diet) and human health. In addition to substantial understanding of nutrition-human-health interaction, bases of 'nutrigenomic' development foster on advent in transcriptomics, genomics, proteomics and metabolomics as well as insight into food as health supplement. Interaction of selected nutrient with associated genes in specific organ or tissue necessary to comprehend that how individual's genetic makeup (DNA transcribed into mRNA and then to proteins) respond to particular nutrient. It provided new opportunities to incorporate natural bioactive compounds into food for specific group of people with similar genotype. As inception of diabetes associated with change in gene expression of, not limited to, protein kinase B, insulin receptor, duodenal homeobox and glucokinase, thus, targeting such proteins by modifying or improving the nutritional availability or uptake may help to devise novel food, supplements, or nutraceuticals. In this article, various aspects of R&D in nutrigenomics are reviewed to ascertain its impact on human health, especially with life-style associated diseases.

Indexed as

CardiovascularDiabetesEthicsInflammationNutrientNutrigenomicsProtein.

Identifiers

PMID27252592
PMCPMC4869012
OpenAlexW2335978051

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.