Evidence map›Paper›PMID 27251687›Full record

ArticleBMJ open2016

Validation of chronic obstructive pulmonary disease (COPD) diagnoses in healthcare databases: a systematic review protocol.

Joseph M Rimland, Iosief Abraha, Maria Laura Luchetta, Francesco Cozzolino, Massimiliano Orso, Antonio Cherubini, Giuseppina Dell'Aquila, Carlos Chiatti, Giuseppe Ambrosio, Alessandro Montedori

Abstract read
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Material Use for Air Leakage Prevention Post-Lung Resection: Insights from Real-World Data in Japan.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joseph M RimlandGeriatrics and Geriatric Emergency Care, Italian National Research Center on Aging, Ancona, Italy.
Iosief AbrahaHealth Planning Service, Regional Health Authority of Umbria, Perugia, Italy.
Maria Laura LuchettaAzienda USL Umbria 1, General Medicine, Perugia, Italy.
Francesco CozzolinoHealth Planning Service, Regional Health Authority of Umbria, Perugia, Italy.
Massimiliano OrsoHealth Planning Service, Regional Health Authority of Umbria, Perugia, Italy.
Antonio CherubiniGeriatrics and Geriatric Emergency Care, Italian National Research Center on Aging, Ancona, Italy.
Giuseppina Dell'AquilaGeriatrics and Geriatric Emergency Care, Italian National Research Center on Aging, Ancona, Italy.
Carlos ChiattiScientific Directorate, Italian National Research Center on Aging, Ancona, Italy.
Giuseppe AmbrosioDepartment of Cardiology, University of Perugia School of Medicine, Perugia, Italy.
Alessandro MontedoriHealth Planning Service, Regional Health Authority of Umbria, Perugia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHealthcare databases are useful sources to investigate the epidemiology of chronic obstructive pulmonary disease (COPD), to assess longitudinal outcomes in patients with COPD, and to develop disease management strategies. However, in order to constitute a reliable source for research, healthcare databases need to be validated. The aim of this protocol is to perform the first systematic review of studies reporting the validation of codes related to COPD diagnoses in healthcare databases. METHODS AND ANALYSIS: MEDLINE, EMBASE, Web of Science and the Cochrane Library databases will be searched using appropriate search strategies. Studies that evaluated the validity of COPD codes (such as the International Classification of Diseases 9th Revision and 10th Revision system; the Real codes system or the International Classification of Primary Care) in healthcare databases will be included. Inclusion criteria will be: (1) the presence of a reference standard case definition for COPD; (2) the presence of at least one test measure (eg, sensitivity, positive predictive values, etc); and (3) the use of a healthcare database (including administrative claims databases, electronic healthcare databases or COPD registries) as a data source. Pairs of reviewers will independently abstract data using standardised forms and will assess quality using a checklist based on the Standards for Reporting of Diagnostic accuracy (STARD) criteria. This systematic review protocol has been produced in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocol (PRISMA-P) 2015 statement. ETHICS AND DISSEMINATION: Ethics approval is not required. Results of this study will be submitted to a peer-reviewed journal for publication. The results from this systematic review will be used for outcome research on COPD and will serve as a guide to identify appropriate case definitions of COPD, and reference standards, for researchers involved in validating healthcare databases. TRIAL REGISTRATION NUMBER: CRD42015029204.

Indexed as

Databases, FactualClinical CodingDelivery of Health CareDisease ManagementHumansInternational Classification of DiseasesMeta-Analysis as TopicPulmonary Disease, Chronic ObstructiveResearch DesignSystematic Reviews as TopicValidation Studies as TopicAdministrative databaseChronic pulmonary obstructive diseaseCOPD algorithmElectronic Health Recordsensitivity and specificitysystematic review

Identifiers

PMID27251687
PMCPMC4893853

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.