ArticleJournal of neurology, neurosurgery, and psychiatry2016
Utility of testing for apraxia and associated features in dementia.
Article in Journal of neurology, neurosurgery, and psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 40 citations in OpenAlex.
- Assessing Limb Apraxia in Quebec: Normative Study of the Brief Battery for the Evaluation of Praxis in Healthy French-Speaking Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026Article
- Apraxic deficits predict general cognitive impairment in patients with biomarker-verified Alzheimer's pathology.Journal of neurology · 2025Article
- The Paper-Toss Test: enhancing bedside recognition of corticobasal syndrome.Frontiers in neurology · 2025Article
- "Try to Build This Bunny as Fast as Possible without Using Red or Pink Bricks": How Simple Assembly Tasks Might Aid in Detecting People with Mild Cognitive Impairment and Dementia.Brain sciences · 2023Article
- Preliminary validation of the apraxia battery for adults-second edition (ABA-2) in Greek patients with dementia.Acta neurologica Belgica · 2022Article
- Impaired Affordance Perception as the Basis of Tool Use Deficiency in Alzheimer's Disease.Healthcare (Basel, Switzerland) · 2022Article
- Psychological and Cognitive Markers of Behavioral Variant Frontotemporal Dementia-A Clinical Neuropsychologist's View on Diagnostic Criteria and Beyond.Frontiers in neurology · 2019Review
- A neuropathologic diagnosis of Alzheimer's disease in an older adult with HIV-associated neurocognitive disorder.Neurocase · 2018Article
- Apraxia profiles-A single cognitive marker to discriminate all variants of frontotemporal lobar degeneration and Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands) · 2018Article
- Association between precuneus volume and autobiographical memory impairment in posterior cortical atrophy: Beyond the visual syndrome.NeuroImage. Clinical · 2018Article
- Can cognitive assessment really discriminate early stages of Alzheimer's and behavioural variant frontotemporal dementia at initial clinical presentation?Alzheimer's research & therapy · 2017Article
- [Networks involved in motor cognition : Physiology and pathophysiology of apraxia].Der Nervenarzt · 2017Review
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5 authors at 3 institutions in 1 country.
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Abstract
introductionExisting literature suggests that the presence or absence of apraxia and associated parietal deficits may be clinically relevant in differential diagnosis of dementia syndromes.
aimThis study investigated the profile of these features in Alzheimer's disease (AD) and frontotemporal dementia (FTD) spectrum disorders, at first presentation.
methodsRetrospective case note analysis was undertaken in 111 patients who presented to the Oxford Cognitive Disorders Clinic, Oxford, UK, including 29 amnestic AD, 12 posterior cortical atrophy (PCA), 12 logopenic primary progressive aphasia (lvPPA), 20 behavioural variant FTD (bvFTD), 7 non-fluent variant PPA (nfvPPA), 6 semantic variant PPA (svPPA) and 25 patients with subjective cognitive impairment (SCI). The clinical features of interest were: limb apraxia, apraxia of speech (AOS), and left parietal symptoms of dyslexia, dysgraphia, and dyscalculia.
resultsThe prevalence of limb apraxia was highest in PCA, amnestic AD, lvPPA and nfvPPA. AOS was only observed in nfvPPA. Associated parietal features were more prevalent in AD spectrum than FTD spectrum disorders. Group comparisons between key differential diagnostic challenges showed that lvPPA and nfvPPA could be significantly differentiated on the presence of left parietal features and AOS, and amnestic AD could be differentiated from bvFTD, svPPA and SCI by limb apraxia. Regression analysis showed that limb apraxia could successfully differentiate between AD and FTLD spectrum disorders with 83% accuracy. DISCUSSION: Disease-specific profiles of limb apraxia and associated deficits can be observed. FTD and AD spectrum disorders can be difficult to differentiate due to overlapping cognitive symptoms, and measures of apraxia, in particular, appear to be a promising discriminator.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.