Evidence map›Paper›PMID 27251410›Full record

ArticleHead & face medicine2016

Spontaneous remission of eosinophilic granuloma of the maxilla after incisional biopsy: a case report.

Alex Vargas, Hernán Ramírez, Pablo Ramírez, Camila Foncea, Bernardo Venegas, Paula Astorga

Open access · goldAbstract readCase Reports
In one paragraph

Article in Head & face medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alex VargasDDS. Associated Professor of the Oncology and Maxillofacial Surgery Department, Medicine Faculty, Pontificia Universidad Católica de Chile, Santiago, Chile. avargasi@uc.cl.
Hernán RamírezDDS. Associated Professor of the Oncology and Maxillofacial Surgery Department, Medicine Faculty, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pablo RamírezAssistant Professor of Hematology Department, Medicine Faculty, Pontificia Universidad Católica de Chile, Santiago, Chile.
Camila FonceaResident of Oral and Maxillofacial Surgery Program, Medicine Faculty, Pontificia Universidad Católica de Chile, Santiago, Chile.
Bernardo VenegasOral Pathologist at the University of Talca and Carlos Van Buren Hospital of Valparaíso, Valparaíso, Chile.
Paula AstorgaObserver of the Oncology and Maxillofacial Surgery Department, Medicine Faculty, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pontificia Universidad Católica de Chile · CLHospital Carlos Van Buren · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLangerhans cell histiocytosis (LCH), previously known as Histiocytosis X, is an infrequent disease that congregates a wide spectrum of clinical presentations with variable systemic involvement. Unification of these diseases under only one category is based on the almost identical histopathologic features of the lesions, but the etiology and proper approach for each presentation remains controversial. The localized alternative of Langerhans cell histiocytosis (LLCH), known as Eosinophilic Granuloma (EG) of bone, is the predominant clinical presentation of LCH. The maxilla is involved in 1 % of the head and neck region cases, representing an uncommon condition in this area. CASE PRESENTATION: In this clinical case report, it is described a case of a 16-year-old male patient with an asymptomatic osteolytic lesion at first upper left molar apical level, a finding detected on control radiographic images was reported as "Monostotic Eosinophilic granuloma of the maxillary bone", which was later confirmed through an incisional biopsy. A surgical excision was initially planned, but finally it was not performed due to a spontaneous healing of the lesion after the incisional biopsy.

conclusionsThe presented case supports a conservative approach in the management of solitary EG of maxillary and mandibular bone lesions and even supports an expectant attitude in the course of treatment given the possibility of a spontaneous regression after the biopsy, especially in small lesions.

Indexed as

AdolescentBiopsy, NeedleBone DiseasesConservative TreatmentEosinophilic GranulomaHumansImmunohistochemistryMaleMaxillaRadiography, PanoramicRare DiseasesRemission, SpontaneousEosinophilic GranulomaLangerhans cell histiocytosisMaxillary bone

Identifiers

PMID27251410
PMCPMC4890254
OpenAlexW2411042036

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.