ArticleBMC surgery2016
Transduodenal ampullectomy provides a less invasive technique to cure early ampullary cancer.
Article in BMC surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Long-term recurrence after endoscopic versus surgical ampullectomy of sporadic ampullary adenomas: a systematic review and meta-analysis.Surgical endoscopy · 2023Pooled it
- A Comparison of Clinical Outcomes between Endoscopic Resection and Surgical Resection in Ampullary Tumors.Medicina (Kaunas, Lithuania) · 2020Pooled it
- Endoscopic Papillectomy for Ampullary Tumors in Older Patients: Balancing Oncologic Benefit and Geriatric Risk.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Surgical outcomes of transduodenal ampullectomy for early-stage ampullary carcinoma: a comparative analysis with pancreaticoduodenectomy.International journal of surgery case reports · 2026Article
- Pushing the Boundaries of Ampullectomy for Benign Ampullary Tumors: 25-Year Outcomes of Surgical Ampullary Resection Associated with Duodenectomy or Biliary Resection.Journal of clinical medicine · 2024Article
- Endoscopic vacuum therapy (eVAC) combined with continuous perianastomotic irrigation for prevention of anastomotic leak after surgical ampullectomy.Langenbeck's archives of surgery · 2024Article
- Updates on the Management of Ampullary Neoplastic Lesions.Diagnostics (Basel, Switzerland) · 2023Review
- Transduodenal resection for duodenal adenomas may be an underutilized tool - A single institution experience.Heliyon · 2022Article
- Transduodenal resection of periampullary neuroendocrine tumor: A case report.Annals of medicine and surgery (2012) · 2022Article
- Surgical ampullectomy: A comprehensive review.World journal of gastrointestinal surgery · 2021Review
- A duodenal ampullary tumor with malignant transformation of papillary polyps: a case report and literature review.The Journal of international medical research · 2021Review
- Microscopic transduodenal excision of an ampullary adenoma: A case report and review of the literature.World journal of clinical cases · 2021Article
- Ampullary Adenocarcinoma: a Mini-Review and a Case Report of a Clinically Stable Disease Patient Treated with Herbal Supplements.Journal of gastrointestinal cancer · 2021Article
- Article
- Systematic Review with Meta-Analysis: Endoscopic and Surgical Resection for Ampullary Lesions.Journal of clinical medicine · 2020Review
- Study Protocol of the ESAP Study: Endoscopic Papillectomy vs. Surgical Ampullectomy vs. Pancreaticoduodenectomy for Ampullary Neoplasm-A Pancreas2000/EPC Study.Frontiers in medicine · 2020Article
- Transduodenal ampullectomy for ampullary tumors - single center experience of consecutive 26 patients.Annals of surgical treatment and research · 2018Article
- Transduodenal ampullectomy for ampullary tumors.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to evaluate the clinical efficiency of transduodenal ampullectomy (TDA) compared to conventional pancreatoduodenectomy (PD) in patients with early ampullary cancers.
methodsWe carried out a retrospective study by reviewing the medical records of 43 patients with early ampullary cancer who underwent either TDA or PD from January 2001 to December 2014. TDA and PD were performed on 22 patients and 21 patients, respectively. Clinical data, perioperative clinical outcomes and prognosis were evaluated. The median follow-up was 75 (range, 38-143) months.
resultsThe sensitivity of intraoperative frozen resection was 100 % (4/4) and 94.9 % (37/39) in patients with pTis and pT1 tumors compared to final histologic diagnoses. The 5-year survival rate of patients with early ampullary cancer was 77.3 % in TDA group and 75.9 % in PD group (P = 0.927). Patients with lymph node metastasis presented a shorter 5-year survival rate (P = 0.014). TDA was associated with lower surgical morbidity (P = 0.033), estimated blood loss (P = 0.002), medical cost (P = 0.028) compared to PD. No pancreatic fistula and surgical mortality occurred in TDA group.
conclusionsTDA could produce satisfactory clinical efficiency in patients fulfilled the following criteria simultaneously: pTis or pT1 stage, tumor size ≤ 2 cm, without lymph node metastasis. To achieve favorable outcomes, intraoperative frozen section examinations should be reliable and resection margins should be negative.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.