ArticleCerebellum (London, England)2017
Resting-State Functional Connectivity Changes Between Dentate Nucleus and Cortical Social Brain Regions in Autism Spectrum Disorders.
Article in Cerebellum (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.
- A Systematic Review of Direct Outputs from the Cerebellum to the Brainstem and Diencephalon in Mammals.Cerebellum (London, England) · 2024Pooled it
- Feasibility and Efficacy of a Virtual Reality Social Prediction Training in Children and Young Adults with Congenital Cerebellar Malformations.Journal of autism and developmental disorders · 2025Trial
- Modulating mental state recognition by anodal tDCS over the cerebellum.Scientific reports · 2022Trial
- Attenuation of social preference and alteration of cortical neurons following adolescent cerebellar nuclei perturbation.Molecular psychiatry · 2026Article
- Probabilistic inference of social presence across brain scales reveals enhanced synaptic efficacy.Communications biology · 2025Article
- Diffusion trajectory of atypical morphological development in autism spectrum disorder.Communications biology · 2025Article
- Functional recruitment and connectivity of the cerebellum is associated with the emergence of Theory of Mind in early childhood.Nature communications · 2025Article
- Multimodal evidence for cerebellar influence on cortical development in autism: structural growth amidst functional disruption.Molecular psychiatry · 2025Article
- Hyperconnectivity and Connectome Gradient Dysfunction of Cerebello-Thalamo-Cortical Circuitry in Alzheimer's Disease Spectrum Disorders.Cerebellum (London, England) · 2025Article
- Cerebellum Lecture: the Cerebellar Nuclei-Core of the Cerebellum.Cerebellum (London, England) · 2024Review
- Intrinsic network abnormalities in children with autism spectrum disorder: an independent component analysis.Brain imaging and behavior · 2024Article
- Dynamics of Cerebral Function in Patients with Acute Cerebellar Infarction.Cerebellum (London, England) · 2024Article
- Both stronger and weaker cerebro-cerebellar functional connectivity patterns during processing of spoken sentences in autism spectrum disorder.Human brain mapping · 2023Article
- Resting-state functional connectivity-based parcellation of the human dentate nucleus: new findings and clinical relevance.Brain structure & function · 2023Review
- [Progress in neural network mechanism of tinnitus using functional magnetic resonance imaging].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023Article
- A neuro-computational social learning framework to facilitate transdiagnostic classification and treatment across psychiatric disorders.Neuroscience and biobehavioral reviews · 2023Review
- Cerebellar contributions to fear-based emotional processing: relevance to understanding the neural circuits involved in autism.Frontiers in systems neuroscience · 2023Review
- Input and output organization of the mesodiencephalic junction for cerebro-cerebellar communication.Journal of neuroscience research · 2022Article
- Cerebellar and basal ganglia motor network predicts trait depression and hyperactivity.Frontiers in behavioral neuroscience · 2022Article
- Cognitive theories of autism based on the interactions between brain functional networks.Frontiers in human neuroscience · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autism spectrum disorders (ASDs) are known to be characterized by restricted and repetitive behaviors and interests and by impairments in social communication and interactions mainly including "theory of mind" (ToM) processes. The cerebellum has emerged as one of the brain regions affected by ASDs. As the cerebellum is known to influence cerebral cortex activity via cerebello-thalamo-cortical (CTC) circuits, it has been proposed that cerebello-cortical "disconnection" could in part underlie autistic symptoms. We used resting-state (RS) functional magnetic resonance imaging (fMRI) to investigate the potential RS connectivity changes between the cerebellar dentate nucleus (DN) and the CTC circuit targets, that may contribute to ASD pathophysiology. When comparing ASD patients to controls, we found decreased connectivity between the left DN and cerebral regions known to be components of the ToM network and the default mode network, implicated in specific aspects of mentalizing, social cognition processing, and higher order emotional processes. Further, a pattern of overconnectivity was also detected between the left DN and the supramodal cerebellar lobules associated with the default mode network. The presented RS-fMRI data provide evidence that functional connectivity (FC) between the dentate nucleus and the cerebral cortex is altered in ASD patients. This suggests that the dysfunction reported within the cerebral cortical network, typically related to social features of ASDs, may be at least partially related to an impaired interaction between cerebellum and key cortical social brain regions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.