Evidence map›Paper›PMID 27250868›Full record

SynthesisInternational journal of impotence research2016

A meta-analysis of extracorporeal shock wave therapy for Peyronie's disease.

L Gao, S Qian, Z Tang, J Li, J Yuan

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in International journal of impotence research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 6 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 6 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. A systematic review of non-surgical management in Peyronie's disease.International journal of impotence research · 2023
    Pooled it
  4. Pooled it
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  7. Trial
  8. Review
  9. State of shock - a systematic review of extracorporeal shockwave therapy in hand surgery.GMS Interdisciplinary plastic and reconstructive surgery DGPW · 2025
    Review
  10. Article
  11. Survey of the quality and origins of websites on penile low-intensity shockwave therapy in Canada.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023
    Article
  12. Article
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  14. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

L GaoThe Andrology Laboratory and Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
S QianThe Andrology Laboratory and Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Z TangThe Andrology Laboratory and Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
J LiThe Andrology Laboratory and Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
J YuanThe Andrology Laboratory and Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficiency of extracorporeal shock wave therapy (ESWT) for Peyronie's disease (PD) has been controversial for a very long time. We aimed to evaluate the efficiency of ESWT for PD and provide possible evidence on the basis of a meta-analysis of existing comparative studies. All controlled studies, including randomized controlled trials (RCTs), cohort studies and case-control studies, that focused on the efficiency of ESWT for PD, were prospectively identified through comprehensive searches of PubMed, the Cochrane Library and Embase databases. We conducted a meta-analysis of these studies. Six studies including 443 patients were selected for the meta-analysis. Pooling data of these studies showed that ESWT could significantly increase the percentage of men with lessening of penile plaques (odds ratio (OR) 2.07, 95% confidence interval (CI) 1.11-3.85, P=0.02), relief of pain (OR 4.46, 95% CI 2.29-8.68, P<0.0001) and complete remission of pain (OR 5.86, 95% CI 2.66-12.92, P<0.0001). However, insignificant differences were found in improvement of penile curvature (OR 1.88, 95% CI 0.97-3.65, P=0.06) and sexual function (OR 2.22, 95% CI 0.69-7.11, P=0.18) between ESWT and placebo groups. Further, similar results were shown for sensitivity and publication bias analysis when only RCTs were included. However, sporadic complications caused by ESWT were reported, but no patient needed additional treatment aside from conservative observation. ESWT may be an effective and safe treatment for lessening of penile plaques and relieving pain for men with PD, but not for improving of penile curvature and sexual function.

Indexed as

High-Energy Shock WavesHumansMalePenile ErectionPenile IndurationPenisTreatment Outcome

Identifiers

PMID27250868
OpenAlexW2414342286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.