Evidence map›Paper›PMID 27250770›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2016

Plasticity of Candida albicans Biofilms.

David R Soll, Karla J Daniels

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Impact of Biofilm Formation by VaginalJournal of fungi (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Optimization ofFrontiers in bioengineering and biotechnology · 2025
    Article
  10. White-opaque switching inMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Gasdermin D kills bacteria.Microbiological research · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Evaluation of the biofilm life cycle betweenFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David R SollDevelopmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, USA david-soll@uiowa.edu.
Karla J DanielsDevelopmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, USA.
University of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida albicans, the most pervasive fungal pathogen that colonizes humans, forms biofilms that are architecturally complex. They consist of a basal yeast cell polylayer and an upper region of hyphae encapsulated in extracellular matrix. However, biofilms formed in vitro vary as a result of the different conditions employed in models, the methods used to assess biofilm formation, strain differences, and, in a most dramatic fashion, the configuration of the mating type locus (MTL). Therefore, integrating data from different studies can lead to problems of interpretation if such variability is not taken into account. Here we review the conditions and factors that cause biofilm variation, with the goal of engendering awareness that more attention must be paid to the strains employed, the methods used to assess biofilm development, every aspect of the model employed, and the configuration of the MTL locus. We end by posing a set of questions that may be asked in comparing the results of different studies and developing protocols for new ones. This review should engender the notion that not all biofilms are created equal.

Indexed as

BiofilmsCandida albicansCandidiasisCatheter-Related InfectionsCatheters, IndwellingCell AdhesionHumans

Identifiers

PMID27250770
PMCPMC4981664
OpenAlexW2417709546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.