Evidence map›Paper›PMID 27250537›Full record

ReviewTherapeutic delivery2016

In pursuit of functional electrospun materials for clinical applications in humans.

Ryan J Stoddard, Arielle L Steger, Anna K Blakney, Kim A Woodrow

Abstract readReview
In one paragraph

Review in Therapeutic delivery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Tailoring the Release of Paclitaxel from Electrospun Nonwovens.International journal of molecular sciences · 2025
    Article
  5. Living Nanofiber-Enabled Cardiac Patches for Myocardial Injury.JACC. Basic to translational science · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. Stable Dried Catalase Particles Prepared by Electrospraying.Nanomaterials (Basel, Switzerland) · 2022
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Bio-Based Electrospun Fibers for Wound Healing.Journal of functional biomaterials · 2020
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan J StoddardUniversity of Washington, Seattle, WA, 98195, USA.
Arielle L StegerUniversity of Washington, Seattle, WA, 98195, USA.
Anna K BlakneyUniversity of Washington, Seattle, WA, 98195, USA.
Kim A WoodrowUniversity of Washington, Seattle, WA, 98195, USA.

Funding

Combination HIV prevention in drug-eluting fibers: designing for efficacy and useR01AI112002 · NIAID · UNIVERSITY OF WASHINGTON · PI WOODROW, KIM A. · 2014 to 2017
$2.3M
NIAID NIH HHS R01 AI112002
6 · The paper itself

Abstract

Electrospinning is a simple, low-cost and versatile approach to fabricate multifunctional materials useful in drug delivery and tissue engineering applications. Despite its emergence into other manufacturing sectors, electrospinning has not yet made a transformative impact in the clinic with a pharmaceutical product for use in humans. Why is this the current state of electrospun materials in biomedicine? Is it because electrospun materials are not yet capable of overcoming the biological safety and efficacy challenges needed in pharmaceutical products? Or, is it that technological advances in the electrospinning process are needed? This review investigates the current state of electrospun materials in medicine to identify both scientific and technological gaps that may limit clinical translation.

Indexed as

Drug Delivery SystemsTissue EngineeringHumansNanofibersPharmaceutical PreparationsPharmaceutical Preparationsclinical applicationsdrug deliveryelectrospinningmedicated nanofibersscale-up fabrication

Identifiers

PMID27250537
PMCPMC6077760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.