ArticleCritical care (London, England)2016
Use of CRB-65 and quick Sepsis-related Organ Failure Assessment to predict site of care and mortality in pneumonia patients in the emergency department: a retrospective study.
Article in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.
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34 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prognostic models for predicting intensive care unit admission or mortality in critically ill adults not yet been admitted to the intensive care unit.The Cochrane database of systematic reviews · 2026Pooled it
- Comparison of Prognostic Accuracy of the quick Sepsis-Related Organ Failure Assessment between Short- & Long-term Mortality in Patients Presenting Outside of the Intensive Care Unit - A Systematic Review & Meta-analysis.Scientific reports · 2018Pooled it
- Role of qSOFA in predicting mortality of pneumonia: A systematic review and meta-analysis.Medicine · 2018Pooled it
- Performance of the quick Sequential (sepsis-related) Organ Failure Assessment score as a prognostic tool in infected patients outside the intensive care unit: a systematic review and meta-analysis.Critical care (London, England) · 2018Pooled it
- Comparison of the Performance Between Sepsis-1 and Sepsis-3 in ICUs in China: A Retrospective Multicenter Study.Shock (Augusta, Ga.) · 2017Trial
- Article
- Comparative Prognostic Performance of qSOFA and SOFA in Emergency Department Patients With Established Septic Shock.Emergency medicine international · 2026Article
- Respiratory National Early Warning Score for 28-day mortality prediction in suspected sepsis patients in the emergency department.BMC emergency medicine · 2025Article
- Assessment of disease severity in hospitalized community-acquired pneumonia by the use of validated scoring systems.BMC pulmonary medicine · 2025Article
- Development and validation of a predictive model for in-hospital mortality from perioperative bacteremia in gastrointestinal surgery.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
- Importance of qSOFA Score in Terms of Prognosis and Mortality in Critical Care Patients.Yonago acta medica · 2024Article
- Article
- Development and Validation of a Prognostic Risk Score System for COVID-19 Inpatients: A Multi-Center Retrospective Study in China.Engineering (Beijing, China) · 2022Article
- Prognostic Performance of Existing Scoring Systems among Critically Ill Patients Requiring Continuous Renal Replacement Therapy: An Observational Study.Journal of clinical medicine · 2021Article
- Semiautomated Glasgow-Blatchford Bleeding Score helps direct bed placement for patients with upper gastrointestinal bleeding.BMJ open gastroenterology · 2020Article
- Reply to TopeliAmerican journal of respiratory and critical care medicine · 2020Article
- Predictive Accuracy of the Quick Sepsis-related Organ Failure Assessment Score in Brazil. A Prospective Multicenter Study.American journal of respiratory and critical care medicine · 2020Observational
- Prognostic Accuracy of Early Warning Scores for Clinical Deterioration in Patients With COVID-19.Frontiers in medicine · 2020Article
- qSOFA score not predictive of in-hospital mortality in emergency patients with decompensated liver cirrhosis.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2019Observational
- Comparison between the Bouchama and Japanese Association for Acute Medicine Heatstroke Criteria with Regard to the Diagnosis and Prediction of Mortality of Heatstroke Patients: A Multicenter Observational Study.International journal of environmental research and public health · 2019Observational
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Abstract
backgroundThe quick Sepsis-related Organ Failure Assessment (qSOFA) is a new screening system for sepsis that has prognostic performance equal to the full SOFA for patients with suspected infection outside the intensive care unit (ICU). The predictive value of qSOFA for mortality and site of care in patients with pneumonia is not clear. The present study was designed to investigate the predictive performance of qSOFA, CRB-65 (confusion, respiratory rate ≥30/minute, systolic blood pressure <90 mmHg or diastolic blood pressure ≤60 mmHg, age ≥65 years) and CRB (confusion, respiratory rate ≥30/minute, systolic blood pressure <90 mmHg or diastolic blood pressure ≤60 mmHg) for mortality, hospitalisation and ICU admission in patients with pneumonia in the emergency department (ED).
methodsRetrospective analyses of published data on adult patients with pneumonia presenting between January 2012 and May 2014 were undertaken. The prevalence of 28-day mortality, hospitalisation and ICU admission were compared with regard to qSOFA, CRB and CRB-65 scores. The performance of these three systems for predicting outcomes was compared.
resultsOf 1641 patients, 861 (53 %) were hospitalised (38 % in a general ward, 15 % in the ICU), and the remaining 780 (47 %) were treated as outpatients or were observed in the ED. Within 28 days, 547 (33 %) of 1641 patients died. CRB-65, CRB and qSOFA scores of patients who died, were hospitalised and admitted to the ICU than those who survived and were not hospitalised or admitted to the ICU (P < 0.001). AUC values of qSOFA for prediction of 28-day mortality, hospitalisation and ICU admission were similar to those for CRB-65 and CRB. Patients with qSOFA scores of 0, 1, 2 and 3 were associated with, respectively, mortality of 16.3 %, 24.4 %, 48.2 % and 68.4 %; prevalence of hospitalisation of 37.2 %, 47.4 %, 61.6 % and 73.7 %; and prevalence of ICU admission of 9.3 %, 9.1 %, 22.4 % and 45.3 %. Patients with qSOFA scores of 2 and 3 had a significantly higher prevalence of mortality and ICU admission than patients with identical CRB-65 scores.
conclusionsqSOFA is better than CRB-65 for identification of a high risk of mortality and requirement of ICU admission.
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