Evidence map›Paper›PMID 27249647›Full record

ArticlePloS one2016

Validation of NINDS-VCI Neuropsychology Protocols for Vascular Cognitive Impairment in Taiwan.

Hsiu-Fen Lin, Chang-Ming Chern, Hui-Mei Chen, Yi-Chun Yeh, Shu-Chih Yao, Mei-Feng Huang, Shuu-Jiun Wang, Cheng-Sheng Chen, Jong-Ling Fuh

Abstract readValidation Study
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Hsiu-Fen LinDepartment of Neurology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chang-Ming ChernDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
Hui-Mei ChenGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Yi-Chun YehGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Shu-Chih YaoDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
Mei-Feng HuangGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Shuu-Jiun WangDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
Cheng-Sheng ChenDepartment of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Jong-Ling FuhDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo validate the three time-difference neuropsychological protocols developed by the National Institute of Health/National Institute of Neurological Disorders and Stroke (NINDS) and the Canadian Stroke Network for assessment of vascular cognitive impairment (VCI) in Mandarin-speaking subjects and to investigate the clinical application of the shortest form.

methodsPatients aged 50 years or older who had a stroke were invited to participate in the study. Clinical diagnosis of VCI was made. The NINDS-VCI Neuropsychology Protocols, 60-, 30-, and two 5-minute protocols, were administered. The criteria validities of the cognitive protocols against the diagnoses of stroke and VCI were determined via Receiver Operating Characteristic (ROC) analysis. The optimal cut-off point for the 5-minute protocols total score was estimated for clinical use in screening.

resultsEighty-three patients and 53 controls were recruited during the study period. Patients with stroke performed more poorly than the control group in the three neuropsychological protocols. Forty-two patients with stroke were diagnosed with VCI. VCI was used as the standard to estimate the criteria validities. The area under the ROC curve was 0.78, 0.80, 0.75, and 0.73 for the 60-, 30-, 5-mintue protocol-A and 5-minute protocol-B, respectively.

conclusionThese modified neuropsychological protocols can be used as valid instruments when performing comprehensive cognitive assessment or for screening of VCI in Taiwan.

Indexed as

AgedCase-Control StudiesFemaleHumansMaleMiddle AgedStrokeTaiwan

Identifiers

PMID27249647
PMCPMC4889053

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.