ArticleNature plants2016
Local auxin metabolism regulates environment-induced hypocotyl elongation.
Article in Nature plants, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed, 165 citations in OpenAlex.
- Nuclear auxin signaling and temperature: perception and response across scales.The New phytologist · 2026Review
- The gut microbial metabolite 3-indolepropionic acid as a functional neuroprotective agent against intracerebral hemorrhage: integrating epidemiological screening with in vivo validation.Metabolic brain disease · 2026Article
- Transcriptome analysis of two rice cultivars highlights the role of auxin- and JA-responsive genes under heat stress.BMC genomics · 2025Article
- Mechanisms of auxin action in plant growth and development.Nature reviews. Molecular cell biology · 2025Review
- Rice Heat Stress Response: Physiological Changes and Molecular Regulatory Network Research Progress.Plants (Basel, Switzerland) · 2025Review
- Cytosolic- and membrane-localized oxidized indole-3-acetic acid formation regulates developmental auxin transients.Plant physiology · 2025Article
- Genome-Wide Analysis of GRETCHEN HAGEN3 Genes and Characterization of IAA-Amido Synthetase GenePlants (Basel, Switzerland) · 2025Article
- Lights, location, action: shade avoidance signalling over spatial scales.Journal of experimental botany · 2025Review
- Dressed Up to the Nines: The Interplay of Phytohormones Signaling and Redox Metabolism During Plant Response to Drought.Plants (Basel, Switzerland) · 2025Review
- Temporal and spatial frameworks supporting plant responses to vegetation proximity.Plant physiology · 2024Article
- Advances in Plant Auxin Biology: Synthesis, Metabolism, Signaling, Interaction with Other Hormones, and Roles under Abiotic Stress.Plants (Basel, Switzerland) · 2024Review
- GIGANTEA adjusts the response to shade at dusk by directly impinging on PHYTOCHROME INTERACTING FACTOR 7 function.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Two Carya Species,Plants (Basel, Switzerland) · 2024Article
- Plant Growth Regulation in Cell and Tissue Culture In Vitro.Plants (Basel, Switzerland) · 2024Review
- Regulation of tissue growth in plants - A mathematical modeling study on shade avoidance response inFrontiers in plant science · 2024Article
- Organ-specific transcriptional regulation by HFR1 and HY5 in response to shade in Arabidopsis.Frontiers in plant science · 2024Article
- Genome-wide association study for temperature response and photo-thermal interaction of flowering time in soybean using a panel of cultivars with diverse maturity groups.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Spatial regulation of plant hormone action.Journal of experimental botany · 2023Review
- Molecular breeding for improvement of photothermal adaptability in soybean.Molecular breeding : new strategies in plant improvement · 2023Article
- Al-induced CsUGT84J2 enhances flavonol and auxin accumulation to promote root growth in tea plants.Horticulture research · 2023Article
13 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 2 institutions in 3 countries.
Funding
Abstract
A hallmark of plants is their adaptability of size and form in response to widely fluctuating environments. The metabolism and redistribution of the phytohormone auxin play pivotal roles in establishing active auxin gradients and resulting cellular differentiation. In Arabidopsis thaliana, cotyledons and leaves synthesize indole-3-acetic acid (IAA) from tryptophan through indole-3-pyruvic acid (3-IPA) in response to vegetational shade. This newly synthesized auxin moves to the hypocotyl where it induces elongation of hypocotyl cells. Here we show that loss of function of VAS2 (IAA-amido synthetase Gretchen Hagen 3 (GH3).17) leads to increases in free IAA at the expense of IAA-Glu (IAA-glutamate) in the hypocotyl epidermis. This active IAA elicits shade- and high temperature-induced hypocotyl elongation largely independently of 3-IPA-mediated IAA biosynthesis in cotyledons. Our results reveal an unexpected capacity of local auxin metabolism to modulate the homeostasis and spatial distribution of free auxin in specialized organs such as hypocotyls in response to shade and high temperature.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.