Evidence map›Paper›PMID 27249209›Full record

ReviewExpert review of clinical immunology2016

Therapeutic options for cutaneous lupus erythematosus: recent advances and future prospects.

Joshua Chang, Victoria P Werth

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of clinical immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Interventions for cutaneous disease in systemic lupus erythematosus.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Article
  3. Article
  4. Tumid lupus masquerading as rosacea.Journal of osteopathic medicine · 2024
    Article
  5. Cutaneous lupus erythematosus: A review of the literature.International journal of women's dermatology · 2019
    Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Joshua Changa Dermatology Section, Corporal Michael J. Crescenz Philadelphia VA Medical Center , Philadelphia , PA , USA.
Victoria P Wertha Dermatology Section, Corporal Michael J. Crescenz Philadelphia VA Medical Center , Philadelphia , PA , USA.
Philadelphia VA Medical Center · USUniversity of Pennsylvania · US

Funding

Treatment of Dermatomyositis with Ajulemic Acid, a Non-Psychoactive CannabinoidR21AR066286 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI WERTH, VICTORIA P · 2014 to 2016
$387k
The role of TNF-Alpha in cutaneous integrityI01BX000706 · VA · PHILADELPHIA VA MEDICAL CENTER · PI WERTH, VICTORIA P · 2013 to 2016
–
BLRD VA I01 BX000706NIAMS NIH HHS R21 AR066286
6 · The paper itself

Abstract

introductionTreatment and prevention are of critical importance in patients with cutaneous lupus erythematosus (CLE), as the disease can have a devastating effect on patient well-being and quality of life. AREAS COVERED: We conducted a selective search of the PubMed database for articles published between December 2010 and November 2015. This review encompasses both non-pharmaceutical (photoprotection, smoking cessation, drug withdrawal, and vitamin D replacement) and pharmaceutical (topicals, antimalarials, immunosuppressives, biologics, etc.) interventions used in the treatment of CLE. Expert Commentary: Recent work has expanded our understanding of established therapies as well as introduced new treatments for consideration, though existing medications still prove inadequate for a subset of patients. Changes in trial design may help to alleviate this issue.

Indexed as

PhototherapyAnimalsCalcineurin InhibitorsClinical Trials as TopicHumansImmunosuppressive AgentsLupus Erythematosus, CutaneousSmoking CessationVitamin DWithholding TreatmentCalcineurin InhibitorsImmunosuppressive AgentsVitamin DantimalarialsbiologicsCutaneous lupus erythematosusCutaneous Lupus Erythematosus Disease Area and Severity IndexTM (CLASITM)immunomodulatorsimmunosuppressivestopical calcineurin inhibitors

Identifiers

PMID27249209
PMCPMC5843480
OpenAlexW2409814223

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.