ArticlePloS one2016
Magnetic Particle / Magnetic Resonance Imaging: In-Vitro MPI-Guided Real Time Catheter Tracking and 4D Angioplasty Using a Road Map and Blood Pool Tracer Approach.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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Who cites it
24 citing papers in PubMed, 94 citations in OpenAlex.
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- Towards clinical magnetic particle imaging: safety measurements of medical implants in a human cadaver model.Communications engineering · 2025Article
- Development and Degradation Study of PLA-Based Medical Implant Markers for Magnetic Particle Imaging.Macromolecular bioscience · 2025Article
- Advances in Vascular Diagnostics using Magnetic Particle Imaging (MPI) for Blood Circulation Assessment.Advanced healthcare materials · 2024Review
- Bare-Metal Stent Tracking with Magnetic Particle Imaging.International journal of nanomedicine · 2024Article
- Real-time multi-contrast magnetic particle imaging for the detection of gastrointestinal bleeding.Scientific reports · 2023Article
- iMPI: portable human-sized magnetic particle imaging scanner for real-time endovascular interventions.Scientific reports · 2023Article
- Heating of Large Endovascular Stents and Stent Grafts in Magnetic Particle Imaging-Influence of Measurement Parameters and Isocenter Distance.Cardiovascular and interventional radiology · 2023Article
- [Magnetic particle imaging : From research to the prospect of clinical use].Radiologie (Heidelberg, Germany) · 2022Review
- Bimodal Interventional Instrument Markers for Magnetic Particle Imaging and Magnetic Resonance Imaging-A Proof-of-Concept Study.Nanomaterials (Basel, Switzerland) · 2022Article
- Magnetic Particle Imaging: In vitro Signal Analysis and Lumen Quantification of 21 Endovascular Stents.International journal of nanomedicine · 2021Article
- Uncovering the Magnetic Particle Imaging and Magnetic Resonance Imaging Features of Iron Oxide Nanocube Clusters.Nanomaterials (Basel, Switzerland) · 2020Article
- In vivo magnetic particle imaging: angiography of inferior vena cava and aorta in rats using newly developed multicore particles.Scientific reports · 2020Article
- Using magnetic particle imaging systems to localize and guide magnetic hyperthermia treatment: tracers, hardware, and future medical applications.Theranostics · 2020Review
- In-Vitro MPI-guided IVOCT catheter tracking in real time for motion artifact compensation.PloS one · 2020Article
- Human-sized magnetic particle imaging for brain applications.Nature communications · 2019Article
- Magnetic particle imaging in vascular medicine.Innovative surgical sciences · 2018Review
- Magnetic particle imaging for radiation-free, sensitive and high-contrast vascular imaging and cell tracking.Current opinion in chemical biology · 2018Review
- Magnetic Particle Imaging-Guided Heating in Vivo Using Gradient Fields for Arbitrary Localization of Magnetic Hyperthermia Therapy.ACS nano · 2018Article
- In vivo tracking and quantification of inhaled aerosol using magnetic particle imaging towards inhaled therapeutic monitoring.Theranostics · 2018Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn-vitro evaluation of the feasibility of 4D real time tracking of endovascular devices and stenosis treatment with a magnetic particle imaging (MPI) / magnetic resonance imaging (MRI) road map approach and an MPI-guided approach using a blood pool tracer. MATERIALS AND
methodsA guide wire and angioplasty-catheter were labeled with a thin layer of magnetic lacquer. For real time MPI a custom made software framework was developed. A stenotic vessel phantom filled with saline or superparamagnetic iron oxide nanoparticles (MM4) was equipped with bimodal fiducial markers for co-registration in preclinical 7T MRI and MPI. In-vitro angioplasty was performed inflating the balloon with saline or MM4. MPI data were acquired using a field of view of 37.3×37.3×18.6 mm3 and a frame rate of 46 volumes/sec. Analysis of the magnetic lacquer-marks on the devices were performed with electron microscopy, atomic absorption spectrometry and micro-computed tomography.
resultsMagnetic marks allowed for MPI/MRI guidance of interventional devices. Bimodal fiducial markers enable MPI/MRI image fusion for MRI based roadmapping. MRI roadmapping and the blood pool tracer approach facilitate MPI real time monitoring of in-vitro angioplasty. Successful angioplasty was verified with MPI and MRI. Magnetic marks consist of micrometer sized ferromagnetic plates mainly composed of iron and iron oxide.
conclusions4D real time MP imaging, tracking and guiding of endovascular instruments and in-vitro angioplasty is feasible. In addition to an approach that requires a blood pool tracer, MRI based roadmapping might emerge as a promising tool for radiation free 4D MPI-guided interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.