Evidence map›Paper›PMID 27249017›Full record

ArticlePloS one2016

cSPider - Evaluation of a Free and Open-Source Automated Tool to Analyze Corticomotor Silent Period.

Skadi Wilke, Dennis Groenveld, Ulrike Grittner, Jonathan List, Agnes Flöel

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Skadi WilkeDepartment of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Dennis GroenveldDepartment of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Ulrike GrittnerCenter for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Jonathan ListDepartment of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Agnes FlöelDepartment of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe corticomotor silent period (CSP), as assessed noninvasively by transcranial magnetic stimulation (TMS) in the primary motor cortex, has been found to reflect intracortical inhibitory mechanisms. Analysis of CSP is mostly conducted manually. However, this approach is time-consuming, and comparison of results from different laboratories may be compromised by inter-rater variability in analysis. No open source program for automated analysis is currently available. METHODS/

resultsHere, we describe cross-validation with the manual analysis of an in-house written automated tool to assess CSP (cSPider). Results from automated routine were compared with results of the manual evaluation. We found high inter-method reliability between automated and manual analysis (p<0.001), and significantly reduced time for CSP analysis (median = 10.3 sec for automated analysis of 10 CSPs vs. median = 270 sec for manual analysis of 10 CSPs). cSPider can be downloaded free of charge.

conclusioncSPider allows automated analysis of CSP in a reliable and time-efficient manner. Use of this open-source tool may help to improve comparison of data from different laboratories.

Indexed as

AutomationAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedMotor CortexReproducibility of ResultsTranscranial Magnetic StimulationYoung Adult

Identifiers

PMID27249017
PMCPMC4889140

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.