ReviewAvicenna journal of phytomedicine
A review on the inhibitory potential of Nigella sativa against pathogenic and toxigenic fungi.
Review in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
10 citing papers in PubMed, 39 citations in OpenAlex.
- Diversity of Ethiopian Black Cumin (Biochemistry research international · 2025Article
- Antifungal activity of essential oils against itraconazole-resistant pathogenicCurrent medical mycology · 2022Article
- Integrated physiological, metabolomic, and proteome analysis ofFrontiers in microbiology · 2022Article
- Article
- Antifungal activities of quince seed mucilage hydrogel decorated with essential oils ofIranian journal of microbiology · 2021Article
- Effect of thymoquinone on Fusobacterium nucleatum‑associated biofilm and inflammation.Molecular medicine reports · 2020Article
- Review
- Therapeutic potential of thymoquinone liposomes against the systemic infection of Candida albicans in diabetic mice.PloS one · 2018Article
- Improving growth performance and health status of meat-type quail by supplementing the diet with black cumin cold-pressed oil as a natural alternative for antibiotics.Environmental science and pollution research international · 2018Article
- In Vitro Evaluation of the Antioxidant, Cytoprotective, and Antimicrobial Properties of Essential Oil from Pistacia vera L. Variety Bronte Hull.International journal of molecular sciences · 2017Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nigella sativa (N. sativa) grows in various parts of the world, particularly in Iran. It has been traditionally used as a folk remedy to treat a number of diseases. The seeds of this plant contain moisture, proteins, carbohydrates, crude fiber, alkaloids, saponins, ash, fixed oils and essential oil. The major components of the essential oil are thymoquinone, p-cymene, trans-anethole, 2-methyl-5(1-methyl ethyl)-Bicyclo[3.1.0]hex-2-en and γ-terpinene. So far, several pharmacological effects such as anti-oxidant, anti-inflammatory, anti-cancer and anti-microbial have been reported for N. sativa or its active compounds. Thymoquinone, thymohydroquinone and thymol are the most active constituents which have different beneficial properties. The oil, extracts and some of N. sativa active components possessed moderate in vitro and in vivo inhibitory activity against pathogenic yeasts, dermatophytes, non-dermatophytic filamentous fungi and aflatoxin-producing fungi. The main morphological changes of pathogenic and toxigenic fungi treated with N. sativa oil were observed in the cell wall, plasma membrane and membranous organelles, particularly in the nuclei and mitochondria. Although this review represents first step in the search for a new anti-fungal drug, the full potential of N. sativa as a fungitoxic agent has not been exploited and necessitates further investigations.
Indexed as
Identifiers
27247919PMC4884215W2216467941What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.