Evidence map›Paper›PMID 27247917›Full record

ReviewAvicenna journal of phytomedicine

Renal injury, nephrolithiasis and Nigella sativa: A mini review.

Parichehr Hayatdavoudi, Abolfazl Khajavi Rad, Ziba Rajaei, Mousa Al-Reza Hadjzadeh

Open access · greenAbstract readReview
In one paragraph

Review in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
12.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Protective Effects of Black Cumin (International journal of molecular sciences · 2021
    Review
  4. Article
  5. GLP-1 mediates the modulating effect of thymoquinone on feeding behaviors in diabetic rats.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019
    Article
  6. Review
  7. Dissecting the Potential Roles ofFrontiers in aging neuroscience · 2018
    Review
  8. The Effects of Hydroalcoholic Extract ofAdvanced biomedical research · 2017
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Parichehr HayatdavoudiNeurocognitive research center & department of physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Abolfazl Khajavi RadNeurogenic inflammation research center & department of physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ziba RajaeiDepartment of physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Mousa Al-Reza HadjzadehNeurocognitive research center & department of physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IRIsfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe incidence and prevalence of kidney stone is increasing worldwide. After the first recurrence the risk of subsequent relapses is higher and the time period between relapses is shortened. Urinary stones can be severely painful and make a huge economic burden. The stone disease may increase the vulnerability of patients to other diseases such as renal failure. Medicinal herbs are rich sources of antioxidants which are increasingly consumed globally for their safety, efficacy and low price. Nigella sativa is a spice plant that is widely used for prevention and treatment of many ailments in Muslim countries and worldwide. This review aims at investigation of the effects of Nigella sativa on renal injury and stone formation. MATERIALS AND

methodsThe scientific resources including PubMed, Scopus, and Google scholar were searched using key words such as: nephrolithiasis, urolithiasis, kidney/renal stone, renal injury, renal failure, urinary retention and black seed, black cumin, Nigella sativa and thymoquinone.

resultsN. sativa and its main component, thymoquinone showed positive effects in prevention or curing kidney stones and renal failure through various mechanism such as antioxidative, anti-inflammatory, anti-eicosanoid and immunomodulatory effects. The putative candidate in many cases has been claimed to be thymoquinone but it seems that at least in part, particularly in kidney stones, the herbal melanin plays a role which requires further investigation to prove.

conclusionN. sativa and its components are beneficial in prevention and curing of renal diseases including nephrolithiasis and renal damages.

Indexed as

Herbal melaninNephrolithiasisNigella sativa LRena failureThymoquinone

Identifiers

PMID27247917
PMCPMC4884213
OpenAlexW2176313507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.